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Health Sciences North Research Institute | Sudbury, Canada

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Leucovorin Calcium

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Active trials

12 of 67 total trials

A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation (HERMES)

This study will be done to see if ziltivekimab can be used to treat people living with heart failure and inflammation. Participants will either get z...

Heart Failure
Drug: Placebo
Drug: Ziltivekimab

The purpose of this study is to evaluate the efficacy and safety of atezolizumab in combination with tiragolumab compared with durvalumab in particip...

Active, not recruiting
Non-small Cell Lung Cancer (NSCLC)
Drug: Tiragolumab
Drug: Durvalumab

This is a global Phase III, randomized, placebo-controlled, double-blind study designed to evaluate the efficacy and safety of adjuvant treatment wit...

Muscle-invasive Bladder Cancer
Drug: Atezolizumab
Other: Placebo

This study will investigate the effect of tirzepatide on the reduction of morbidity and mortality in adults living with obesity and provide additiona...

Active, not recruiting
Drug: Placebo
Drug: Tirzepatide

The purpose of this study is to demonstrate the efficacy of 9-valent extraintestinal pathogenic Escherichia coli vaccine (ExPEC9V) compared to placeb...

Invasive Extraintestinal Pathogenic Escherichia Coli Disease (IED) Prevention
Biological: ExPEC9V
Other: Placebo

Researchers are looking for a better way to prevent an ischemic stroke which occurs when a blood clot travelled to the brain in people who within the...

High-risk Transient Ischemic Attack
Acute Non-cardioembolic Ischemic Stroke
Drug: Asundexian (BAY2433334)
Drug: Placebo

Sometimes, cancer patients receive an initial treatment, followed by additional treatment to lower the chance of cancer coming back. The standard or...

Active, not recruiting
Oropharyngeal Squamous Cell Carcinoma
Drug: Durvalumab
Drug: Tremelimumab

Durvalumab is a new type of drug for many kinds of cancer. It is considered "immunotherapy" and not "chemotherapy". Laboratory tests show that it wor...

Active, not recruiting
Lung Cancer Metastatic
Drug: Durvalumab
Drug: Tremelimumab

The purpose of this study is to assess the efficacy and safety of stereotactic body radiotherapy (SBRT) plus pembrolizumab (MK-3475) in the treatment...

Active, not recruiting
Non-Small Cell Lung Cancer
Biological: Pembrolizumab
Drug: Placebo

The purpose of this study is to assess the efficacy and safety of the combination of pembrolizumab (MK-3475) and enzalutamide in the treatment of men...

Active, not recruiting
Prostatic Neoplasms
Drug: Placebo
Biological: Pembrolizumab

The current study will compare pembrolizumab (MK-3475) plus maintenance olaparib, vs pembrolizumab plus maintenance pemetrexed for the treatment of n...

Active, not recruiting
Carcinoma, Non-squamous Non-small-cell Lung
Drug: Carboplatin
Drug: Cisplatin

The purpose of this study is to find out what effects durvalumab has on bladder cancer, combined with treatment after completion of surgery, chemothe...

Active, not recruiting
Bladder Cancer
Drug: Durvalumab

Trial sponsors

National Cancer Institute (NCI) logo
Merck Sharp & Dohme (MSD) logo
Population Health Research Institute (PHRI) logo
Roche logo
Alliance for Clinical Trials in Oncology logo
Boehringer Ingelheim logo

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