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Hoag Memorial Hospital Presbyterian | Newport Beach, CA

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Enzalutamide
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Active trials

58 of 169 total trials

177Lu-PSMA-I&T for Metastatic Castration-Resistant Prostate Cancer

A Multi-Center, Open-Label, Randomized Phase 3 Trial Comparing the Safety and Efficacy of 177Lu-PSMA-I\&T versus Hormone Therapy in Patients with Met...

Active, not recruiting
Metastasis From Malignant Tumor of Prostate
Drug: Abiraterone with Prednisone or Enzalutamide
Drug: 177Lu-PSMA-I&T

The goal of this clinical trial is to test CPO301, a type of drug called an antibody drug conjugate in adult patients with advanced or metastatic sol...

Enrolling
Cancer, Lung
Cancer
Drug: CPO301

A randomized controlled trial (RCT) to assess the safety and efficacy of use of Control-IQ technology in adults with type 2 diabetes using basal-bolu...

Active, not recruiting
Type 2 Diabetes Treated With Insulin
Device: Standard Therapy plus continuous glucose monitoring (CGM)
Device: t:slim X2 insulin pump with Control-IQ technology 1.5 and Dexcom G6 CGM

This open-label, exploratory study is designed to evaluate the safety and efficacy of targeted therapies or immunotherapy as single agents or combina...

Active, not recruiting
Metastatic Colorectal Cancer
Drug: Inavolisib
Drug: FOLFIRI

The purpose of this study is to assess the safety, tolerability, and recommended dose(s) of BMS-986340 as monotherapy and in combination with nivolum...

Enrolling
Ovarian Neoplasms
Melanoma
Drug: BMS-986340
Drug: BMS-936558-01

A Phase 2, Multicenter, Open-Label Study of DKN-01 in Combination with Tislelizumab ± Chemotherapy as First-Line or Second-Line Therapy in Adult Pati...

Active, not recruiting
Gastric Cancer
GastroEsophageal Cancer
Drug: Capecitabine 1000mg/ m2 BID
Drug: DKN-01 600mg

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.Additional part...

Active, not recruiting
Alzheimer Disease
Drug: Donanemab
Drug: Placebo

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor activity...

Enrolling
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

The purpose of this study is to assess the safety, tolerability, and efficacy of BMS-986158 alone and in combination with either Ruxolitinib or Fedra...

Active, not recruiting
Myelofibrosis
Drug: Ruxolitinib
Drug: BMS-986158

The purpose of this study is to learn about the safety and how effective the study medicine (PF-07220060) plus fulvestrant is compared to the study d...

Enrolling
Advanced or Metastatic Breast Cancer
Drug: Everolimus
Drug: Fulvestrant

The purpose of this clinical trial is to learn about the safety, extent of the side effects, and immune responses of the study vaccine (called varian...

Enrolling
COVID-19
SARS-CoV-2 Virus
Biological: Variant-adapted BNT162b2 (Omicron XBB.1.5) 3 microgram dose
Biological: Variant-adapted BNT162b2 (Omicron XBB.1.5) 10 microgram dose

The primary objective of this study is to verify the clinical benefit of monthly doses of aducanumab in slowing cognitive and functional impairment a...

Active, not recruiting
Alzheimer's Disease
Drug: Placebo
Drug: Aducanumab

This is a multicenter, randomized, placebo-controlled study to evaluate the long-term efficacy and safety of ABX464 50mg and 25mg administered once d...

Enrolling
Ulcerative Colitis
Drug: ABX464
Drug: Placebo

This is a multicenter, randomized, placebo controlled study to evaluate the efficacy and safety of ABX464 given at 25 or 50 mg QD in inducing clinica...

Enrolling
Ulcerative Colitis
Drug: Placebo
Drug: ABX464

The primary purpose of this study is to determine whether treatment with lecanemab is superior to placebo on change from baseline of the Preclinical...

Enrolling
Preclinical Alzheimer's Disease
Early Preclinical Alzheimer's Disease
Drug: Lecanemab
Drug: Placebo

The objective of this study is to establish the safety and effectiveness of the Edwards SAPIEN X4 Transcatheter Heart Valve (THV) in subjects who are...

Enrolling
Aortic Valve Stenosis
Aortic Valve Insufficiency
Device: SAPIEN X4 THV

The objective of this study is to establish the safety and effectiveness of the Edwards SAPIEN X4 Transcatheter Heart Valve (THV) in subjects with sy...

Enrolling
Aortic Stenosis, Severe
Device: SAPIEN X4 THV

This is a research study to evaluate the safety of an investigational autologous cell product obtained from participant's own adipose tissue as a pos...

Enrolling
Alzheimer Disease
Biological: RB-ADSC

This is a double-blind study in which approximately 99 study patients will be randomized in a 2:1 ratio to receive either AVOVA-1 or MC. Patients eli...

Active, not recruiting
Stage III Ovarian Carcinoma
Primary Peritoneal Carcinoma
Biological: MC
Biological: AVOVA-1

This is a single-arm, open-label phase II clinical trial in which approximately 55 patients with newly diagnosed glioblastoma (GBM) will be enrolled...

Active, not recruiting
Newly Diagnosed Glioblastoma
Biological: AV-GBM-1

Trial sponsors

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Pfizer logo
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Edwards Lifesciences logo
University of Southern California logo
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