Horizon Clinical Research | La Mesa, CA

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Active trials

5 of 5 total trials

A Safety and Efficacy Study of Anti-inflammatory (Canakinumab) and Cartilage Stimulating (LNA043) Drugs Injected Into the Knee Joint of Participants With Knee Osteoarthritis (OA)

The study will establish safety and efficacy of canakinumab and LNA043 in patients with knee osteoarthritis (OA).

Active, not recruiting
Knee Osteoarthritis
Biological: LNA043
Other: Placebo to canakinumab

The goal of this clinical trial is to examine the effect of a single autologous, intra-articular injection of MFat versus saline injection for the tr...

Knee Osteoarthritis
Osteo Arthritis Knee
Drug: Saline Injection
Device: Microfragmented Adipose Tissue derived using the Lipogems® System

The purpose of the present study is to assess the efficacy of secukinumab 300 mg s.c. (subcutaneous) compared to placebo, each in combination with st...

Active, not recruiting
Rotator Cuff Tendinopathy
Drug: Secukinumab
Drug: Placebo

This is a double-blinded, two-arm, phase II study to assess efficacy, safety and tolerability of DFV890 in participants with symptomatic knee osteoar...

Symptomatic Knee Osteoarthritis
Drug: Placebo
Drug: DFV890

Primary Objective: To assess the efficacy of ZILRETTA on pain following an intra-articular (IA) injection in subjects with glenohumeral osteoarthriti...

Glenohumeral Osteoarthritis
Other: Placebo

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