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Horizon Clinical Research | La Mesa, CA

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dHACM
Acetaminophen
Ibuprofen
DHACM
Secukinumab
HTX-011
DFV890

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Active trials

12 of 17 total trials

A Study to Evaluate the Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee

This study is being conducted to evaluate the efficacy and safety of ASA compared to placebo in the management of osteoarthritis (OA) symptoms of the...

Enrolling
Knee Osteoarthritis
Biological: Amniotic Suspension Allograft
Drug: Placebo

The study is a randomized, prospective, multicenter, controlled clinical trial of the Episealer Knee System. The Episealer Knee System is intended fo...

Active, not recruiting
Degenerative Lesion of Articular Cartilage of Knee
Procedure: Microfracture
Device: Episealer Knee System

It is hypothesized that a single Intra-articular Injection of TTAX03, 100mg in 2mL of saline, will have more benefit with respect to the proportion o...

Active, not recruiting
Knee Arthritis
Knee Pain Chronic
Biological: Saline
Biological: TTAX03

The goal of this clinical trial is to examine the effect of a single autologous, intra-articular injection of MFat versus saline injection for the tr...

Enrolling
Knee Osteoarthritis
Osteo Arthritis Knee
Drug: Saline Injection
Device: Microfragmented Adipose Tissue derived using the Lipogems® System

To evaluate the safety and efficacy of implanting pellet-type extracellular matrix-associated autologous chondrocytes (CartiLife®) obtained by cultiv...

Enrolling
Articular Cartilage Degeneration
Articular Cartilage Defect
Drug: Autologous Chondrocyte Implantation (CartiLife®)

Multicenter, open-label, controlled, non-randomized, double arm trial with a prospective treatment arm (GelrinC). This study compares the efficacy an...

Active, not recruiting
Articular Cartilage Defects in the Knee Joint
Other: Microfracture historical control arm
Device: GelrinC

The purpose of the present study is to assess the efficacy of secukinumab 300 mg s.c. (subcutaneous) compared to placebo, each in combination with st...

Active, not recruiting
Rotator Cuff Tendinopathy
Drug: Secukinumab
Drug: Placebo

This is a double-blinded, two-arm, phase II study to assess efficacy, safety and tolerability of DFV890 in participants with symptomatic knee osteoar...

Active, not recruiting
Symptomatic Knee Osteoarthritis
Drug: Placebo
Drug: DFV890

This study evaluates the efficacy and safety of a single IA injection of various RTX doses, Zilretta or placebo for the treatment of pain due to mode...

Active, not recruiting
Knee Pain Chronic
Knee Osteoarthritis
Drug: Zilretta
Drug: Resiniferatoxin

The Hyalex Early Feasibility Study is a prospective, multicenter, open-label, single-arm, 2-phase early feasibility study to evaluate the safety and...

Enrolling
Cartilage Injury
Cartilage Damage
Device: Hyalex Knee Cartilage System

The NUsurface® Meniscus Implant SUN Clinical Trial is a multi-center, single-arm, prospective, open label, non-randomized, observational clinical tri...

Active, not recruiting
Post-Meniscectomy Pain Syndrome
Osteoarthritis, Knee
Device: NUsurface® Meniscus Implant

Primary Objective: To assess the efficacy of ZILRETTA on pain following an intra-articular (IA) injection in subjects with glenohumeral osteoarthriti...

Enrolling
Glenohumeral Osteoarthritis
Other: Placebo
Drug: ZILRETTA

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