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Horizon Research Group LLC | Coral Gables, FL

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RGLS8429
APL-2
VX-147

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Active trials

2 of 3 total trials

A Study of RGLS8429 in Patients With Autosomal Dominant Polycystic Kidney Disease

Primary Objectives* To assess the safety and tolerability of RGLS8429* To assess the impact of RGLS8429 on ADPKD biomarkersSecondary Objectives* To a...

Enrolling
ADPKD
Polycystic Kidney, Autosomal Dominant
Drug: RGLS8429
Drug: Placebo

The purpose of this study is to evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants...

Enrolling
Proteinuric Kidney Disease
Drug: Placebo
Drug: VX-147

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