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Horizon Research Group LLC | Coral Gables, FL

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Top treatments

BI 690517
VX-147
RDX013
RGLS8429
APL-2
MK-2060
Empagliflozin

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Active trials

3 of 6 total trials

A Study of RGLS8429 in Patients With Autosomal Dominant Polycystic Kidney Disease

Primary Objectives* To assess the safety and tolerability of RGLS8429* To assess the impact of RGLS8429 on ADPKD biomarkersSecondary Objectives* To a...

Enrolling
ADPKD
Polycystic Kidney, Autosomal Dominant
Drug: Placebo
Drug: RGLS8429

The purpose of this study is to evaluate the efficacy and safety of two different doses of MK-2060 (a monoclonal antibody against Factor XI) in end s...

Active, not recruiting
End-Stage Renal Disease
End-Stage Kidney Disease
Drug: MK-2060
Drug: Placebo

The purpose of this study is to evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of VX-147 in adult and pediatric participants...

Enrolling
Proteinuric Kidney Disease
Drug: Placebo
Drug: VX-147

Trial sponsors

A
Ardelyx logo
Boehringer Ingelheim logo
Merck Sharp & Dohme (MSD) logo
R
Vertex Pharmaceuticals logo

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