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Hospital da Luz | Lisboa

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Empagliflozin
Vicadrostat
9-ING-41
Durvalumab
BI 690517
Estrogen
Ribociclib
Teriflunomide
Giredestrant
Atezolizumab

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Active trials

10 of 16 total trials

9-ING-41 in Patients with Advanced Cancers

GSK-3β is a potentially important therapeutic target in human malignancies. The Actuate 1801 Phase 1/2 study is designed to evaluate the safety and e...

Active, not recruiting
Neoplasm of Lung
Neoplasms Pancreatic
Drug: Gemcitabine - 21 day cycle
Drug: 9-ING-41

This is a Phase III, global, randomized, open-label, multicenter, study evaluating the efficacy and safety of adjuvant giredestrant compared with end...

Active, not recruiting
Early Breast Cancer
Drug: Endocrine Therapy of Physician's Choice
Drug: Abemaciclib

The purpose of this study is to assess the efficacy, safety, and immunogenicity of ABP 206 compared with Nivolumab in Subjects with Treatment-Naïve U...

Enrolling
Melanoma
Drug: ABP 206
Drug: Nivolumab

A study to evaluate the efficacy and safety of fenebrutinib on disability progression and relapse rate in adult participants with RMS. Eligible parti...

Active, not recruiting
Relapsing Multiple Sclerosis
Drug: Placebo
Drug: Fenebrutinib

This study is open to adults who are at least 18 years old and have a body mass index (BMI)bof 27 kg/m2 or more. People can take part if they have ca...

Active, not recruiting
Obesity
Drug: Placebo
Drug: survodutide

This study is open to adults with type 2 diabetes, high blood pressure, and cardiovascular disease. People can join the study if they have these cond...

Enrolling
Hypertension
Cardiovascular Diseases
Drug: Placebo matching Vicadrostat
Drug: Vicadrostat

The ICONIC-M study is a multicenter randomized controlled study to assess patient response to CRT comparing ECGI map guided left ventricular lead pla...

Enrolling
Heart Failure With Reduced Ejection Fraction
Device: Pre-implantation planning
Device: Post-implantation assessment

This is an open-label, multicenter international trial in men and women with primary operable HR+/HER2-, ki67≥20%, grade 2 or 3 and stage II breast c...

Enrolling
Breast Cancer Stage II
Drug: Ribociclib (adjuvant)
Drug: Chemotherapy (adjuvant)

The study looks at how liraglutide works on participant's body weight. Researchers will look at how liraglutide can help children with obesity to los...

Active, not recruiting
Obesity
Drug: Liraglutide
Drug: Placebo
Locations recently updated

This clinical trial is designed to assess the efficacy and safety of the triplet combination of trastuzumab deruxtecan (ENHERTU, T-DXd, DS-8201a) plu...

Enrolling
Gastroesophageal Junction Cancer
Gastric Cancer
Drug: Chemotherapy
Drug: pembrolizumab

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