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Finerenone
AZ-3102
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Active trials

9 of 14 total trials
Locations recently updated

A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis (ICONIC-UC)

The purpose of this protocol is to evaluate the efficacy (how well it works), safety and tolerability of oral icotrokinra as therapy in adult and ado...

Enrolling
Colitis, Ulcerative
Drug: Icotrokinra
Drug: Placebo
Recently updated

The purpose of this study is to evaluate whether the addition of selexipag to standard of care treatment delays disease progression in children with...

Active, not recruiting
Hypertension, Pulmonary
Drug: SOC: Phosphodiesterase type 5 (PDE-5) inhibitor
Drug: Standard of Care (SOC): Endothelin receptor antagonist

The purpose of this study is to evaluate efficacy of golimumab in inducing clinical remission as assessed by the Mayo score, in pediatric participant...

Active, not recruiting
Colitis, Ulcerative
Drug: Infliximab
Drug: Golimumab
Locations recently updated

An 18-month double-blind, randomized, placebo-controlled, multicenter, Phase 3 study to evaluate the safety and efficacy of oral nizubaglustat (AZ-31...

Enrolling
Gangliosidosis, GM1
Gangliosidoses, GM2
Drug: AZ-3102
Drug: Placebo
Locations recently updated

An 18-month double-blind, randomized, placebo-controlled, multicenter, Phase 3 study to evaluate the safety and efficacy of oral nizubaglustat (AZ-31...

Enrolling
Niemann-Pick Type C Disease
Drug: Nizubaglustat
Drug: Placebo
Status recently updated

Researchers are looking for a better way to treat children and young adults who have heart failure with left ventricular systolic dysfunction (LVSD)....

Not yet enrolling
Enrolling
Heart Failure (Pediatric)
Left Ventricular Systolic Dysfunction
Drug: Finerenone (Kerendia, BAY94-8862)

Researchers are looking for a better way to treat children who have chronic kidney disease (CKD), which is long-term kidney disease, and proteinuria,...

Enrolling
Chronic Kidney Disease
Proteinuria
Drug: Finerenone (Kerendia, BAY94-8862)

Researchers are looking for a better way to treat children who have heart failure with left ventricular systolic dysfunction (LVSD). Heart failure is...

Enrolling
Left Ventricular Systolic Dysfunction
Heart Failure (Pediatric)
Drug: Placebo
Drug: Finerenone (Kerendia, BAY94-8862)

Researchers are looking for a better way to treat children who have chronic kidney disease (CKD), which is long-term kidney disease, and proteinuria,...

Enrolling
Chronic Kidney Disease
Proteinuria
Drug: Finerenone (Kerendia, BAY94-8862)
Drug: Placebo

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