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Finerenone
AZ-3102
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Active trials

9 of 13 total trials

A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension (SALTO)

The purpose of this study is to evaluate whether the addition of selexipag to standard of care treatment delays disease progression in children with...

Active, not recruiting
Hypertension, Pulmonary
Drug: Selexipag
Drug: Placebo

The purpose of this study is to evaluate efficacy of golimumab in inducing clinical remission as assessed by the Mayo score, in pediatric participant...

Active, not recruiting
Colitis, Ulcerative
Drug: Infliximab
Drug: Golimumab
Locations recently updated

An 18-month double-blind, randomized, placebo-controlled, multicenter, Phase 3 study to evaluate the safety and efficacy of oral nizubaglustat (AZ-31...

Enrolling
Gangliosidosis, GM1
Gangliosidoses, GM2
Drug: AZ-3102
Drug: Placebo
Recently updated

An 18-month double-blind, randomized, placebo-controlled, multicenter, Phase 3 study to evaluate the safety and efficacy of oral nizubaglustat (AZ-31...

Enrolling
Niemann-Pick Type C Disease
Drug: Nizubaglustat
Drug: Placebo

Researchers are looking for a better way to treat children and young adults who have heart failure with left ventricular systolic dysfunction (LVSD)....

Begins enrollment in 2 months
Heart Failure (Pediatric)
Left Ventricular Systolic Dysfunction
Drug: Finerenone (Kerendia, BAY94-8862)

Researchers are looking for a better way to treat children who have chronic kidney disease (CKD), which is long-term kidney disease, and proteinuria,...

Enrolling
Chronic Kidney Disease
Proteinuria
Drug: Finerenone (Kerendia, BAY94-8862)

Researchers are looking for a better way to treat children who have heart failure with left ventricular systolic dysfunction (LVSD). Heart failure is...

Not yet enrolling
Left Ventricular Systolic Dysfunction
Heart Failure (Pediatric)
Drug: Placebo
Drug: Finerenone (Kerendia, BAY94-8862)

Researchers are looking for a better way to treat children who have chronic kidney disease (CKD), which is long-term kidney disease, and proteinuria,...

Enrolling
Chronic Kidney Disease
Proteinuria
Drug: Finerenone (Kerendia, BAY94-8862)
Drug: Placebo

This phase 2 is a randomized, double-blind, placebo controlled, 12 weeks study with daily oral administration of AZ-3102 aiming to evaluate the safet...

Active, not recruiting
Niemann-Pick Disease, Type C
GM2 Gangliosidosis
Drug: AZ-3102 (Dose 1)
Drug: AZ-3102 (Dose 2)

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