Unidad de Hemofilia

Hospital Sotero del Rio

Ulcerative Colitis

Colitis

Ulcer

Stomach Cancer

Premature Birth

Type 2 Diabetes Mellitus

Diseases Premature Infant

Critical Illness

COVID-19

Diabetes Mellitus

Etrasimod

Linagliptin

Arena Pharmaceuticals

Boehringer Ingelheim

Genova Inc.

University of Miami

Hospital Dr Sotero del Rio

Oftalmologia Hospital Sotero del Rio

Pontificia Universidad Catolica de Chile

condition

allSponsorName

gender

Male

Female

overallStatus

Recruiting

Not yet recruiting

Active, not recruiting

Enrolling by invitation

Completed

Terminated

Withdrawn

Suspended

Unknown

type

Interventional

Observational

Expanded Access

phase

Early Phase 1

Phase 1

Phase 2

Phase 3

Phase 4

Not Applicable

funderTypes

Industry

Other U.S. Federal agency

All others

ageGroup

Child (birth-17)

Adult (18-64)

Older Adult (65+)

This study is a randomized, double-blind, multicenter, placebo-controlled trial to evaluate the safety and efficacy of a novel therapeutic agent, Novaferon, in hospitalized adult patients diagnosed with COVID-19. The study is comprised of two cohorts:

* Cohort A: This is a blinded safety lead-in comprising two arms. 40 patients will be randomized on a 1:1 basis to receive either Novaferon or matched placebo via a commercial nebulizer, plus Standard of Care (SOC)
* Cohort B: This is the main portion of the study, which comprises two arms. Up to 874 patients will be randomized on a 1:1 basis to receive either Novaferon or matched placebo via a commercial nebulizer, plus SOC

Phase 3 Inhaled Novaferon Study in Hospitalized Patients With Moderate to Severe COVID-19

Hospital Sotero del Rio | Unidad de Hemofilia

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Active trials

Phase 3 Inhaled Novaferon Study in Hospitalized Patients With Moderate to Severe COVID-19 (NOVATION-1)

Trial sponsors