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Hull University Teaching Hospitals NHS Trust | Hull Royal Infirmary - Academic Renal Research Department

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Active trials

9 of 37 total trials

A Study of Guselkumab in Participants With Fistulizing, Perianal Crohn's Disease (FUZION CD)

The purpose of this study to evaluate the clinical efficacy of guselkumab in fistulizing, perianal Crohn's disease and to assess the overall safety o...

Enrolling
Perianal Crohns Disease
Fistulizing Crohns Disease
Drug: Guselkumab
Drug: Placebo

The study consists of 4 sub-studies, as follows:* Sub-study 1 (Randomized, double-blind, placebo controlled study) to evaluate the efficacy and safet...

Active, not recruiting
Crohn's Disease
Drug: Placebo for Risankizumab IV
Drug: Risankizumab SC
Locations recently updated

Study WR42221 is a Phase IIIb, global, multicenter, randomized, visual assessor-masked study designed to assess the efficacy, safety, and pharmacokin...

Enrolling
Neovascular Age-related Macular Degeneration (nAMD)
Device: Port Delivery System with Ranibizumab
Drug: Ranibizumab

This study is researching an experimental drug called REGN3767, also known as fianlimab (R3767), when combined with another medication called REGN281...

Enrolling
Melanoma
Drug: Cemiplimab
Drug: Placebo

The aim of the study is to compare performance and safety of a newly developed 14-gauge open-tip pulsed biopsy needle with a conventional 14-gauge co...

Enrolling
Breast Cancer
Device: Open-tip pulsed needle biopsy (NeoNavia Biopsy System)
Device: Core needle biopsy (CNB)

COVID-19 (SARS-CoV2 virus) was declared a global pandemic by the WHO on 11th March 2020. Currently there are no drugs proven to prevent COVID-19 or t...

Enrolling
Covid19
Drug: Placebo
Drug: Sotrovimab

An Open Label Long-Term Study to Evaluate the Safety and Tolerability of Seladelpar in Subjects with Primary Biliary Cholangitis (PBC)

Enrolling
Primary Biliary Cirrhosis
Drug: Seladelpar 10 mg Capsule
Drug: Seladelpar 5 mg Capsule

Study to evaluate the efficacy, safety, and tolerability of investigational drug obeticholic acid (OCA) in combination with the investigational drug...

Active, not recruiting
Primary Biliary Cholangitis
Drug: Bezafibrate 400 mg Placebo
Drug: Bezafibrate 200 MG

The investigators propose to create a prospective Crohn Disease cohort, where patients receiving the most up-to-date therapies with a treat-to-target...

Enrolling
Crohn Disease
Diagnostic Test: MRE

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