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Active trials

8 of 13 total trials

A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

This is a double-blind, randomized, multiregion, comparative phase Ⅲ clinical study designed to evaluate the efficacy and safety of HLX22 in combinat...

Enrolling
Gastric Cancer
Monoclonal Antibody
Drug: HLX22
Drug: Pembrolizumab

This is a Phase III, global, randomized, open-label, multicenter, study evaluating the efficacy and safety of adjuvant giredestrant compared with phy...

Active, not recruiting
Early Breast Cancer
Drug: Giredestrant
Drug: LHRH Agonist

This study is being done to find out if zanidatamab, when given with chemotherapy plus or minus tislelizumab, is safe and works better than trastuzum...

Active, not recruiting
Gastroesophageal Adenocarcinoma
Gastric Neoplasms
Drug: Tislelizumab
Drug: Capecitabine

The primary objective of this trial is to demonstrate pharmacokinetic (PK) similarity of ABP 234 compared with the pembrolizumab reference product (K...

Active, not recruiting
Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer
Drug: ABP 234
Drug: Pembrolizumab (EU)

The main aim of this study is to find out how well elritercept works to improve anemia in participants with myelofibrosis (MF) who are taking ruxolit...

Enrolling
Anemia
Myelofibrosis
Drug: Placebo
Drug: Elritercept

This is a Phase III, randomized, open-label multicenter study that will evaluate the efficacy and safety of giredestrant compared with fulvestrant, b...

Enrolling
Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer
Diagnostic Test: FoundationOne Liquid CDx Assay (F1LCDx)
Drug: Giredestrant

The primary objective of this study is to demonstrate pharmacokinetic (PK) similarity ABP 234 with pembrolizumab.

Active, not recruiting
Early-stage Non-squamous Non-small Cell Lung Cancer (NSCLC)
Drug: ABP 234
Drug: Pembrolizumab

The purpose of this study is to assess the efficacy and safety of RO7771950 in combination with trastuzumab and capecitabine, compared to tucatinib i...

Enrolling
HER2-positive Breast Cancer
Drug: Capecitabine
Drug: Tucatinib

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