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Icon Cancer Centre | South Brisbane, Australia

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Platinum
Pembrolizumab
Budigalimab
ABBV-181
Livmoniplimab
ABBV-151
Paclitaxel
Veliparib
Pomalidomide
Atezolizumab

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Active trials

10 of 19 total trials
Locations recently updated

A First-in-Human Study of MEN2501 in Participants With Platinum-Resistant Ovarian Cancer

This is a first-in-human, open-label, dose-escalation, dose-optimization trial designed to evaluate the safety, tolerability, pharmacokinetics, pharm...

Enrolling
Platinum-resistant Ovarian Cancer
Drug: MEN2501

This study will assess the safety and efficacy of VS-7375 alone and in combination with cetuximab in patients with metastatic KRAS G12D - mutated Pan...

Enrolling
G12D Mutated KRAS
Pancreatic Ductal Adenocarcinoma (PDAC)
Drug: VS-7375
Drug: cetuximab

A study designed tocompare progression-free survival (PFS) in participants with t(11;14)-positive MM treated with venetoclax in combination with dexa...

Active, not recruiting
Multiple Myeloma
Drug: Pomalidomide
Drug: Venetoclax

The objective of this study is to investigate the PK, PD, safety, and tolerability of ivosidenib in adult participants with IDH1-mutated malignancies...

Enrolling
IDH1-Mutated Malignancies
Drug: Ivosidenib Oral Tablet

A study evaluating the safety, pharmacokinetics (PK), pharmacodynamics, and preliminary efficacy of ABBV-927 with ABBV-368, Budigalimab (ABBV-181) an...

Active, not recruiting
Advanced Solid Tumors
Non-small-cell-lung-cancer (NSCLC)
Drug: ABBV-368
Drug: ABBV-927

This clinical study is testing whether a new combination of medicines (DSP107 and atezolizumab) is more effective and safer than an existing treatmen...

Enrolling
Colorectal Cancer
Drug: Fruquintinib
Drug: DSP107 + Atezolizumab

A Phase 3, randomized, 2-arm, open-label, multicenter, stratified study of soquelitinib versus physician's choice standard of care (SOC) treatment (s...

Enrolling
Lymphoma, T-Cell
Nodal Peripheral T-Cell Lymphoma With TFH Phenotype
Drug: Pralatrexate
Drug: Belinostat

This is a global, multicenter, randomized, open-label study. The main objective of the study is to measure the clinical activity and safety of zelene...

Active, not recruiting
Metastatic Urothelial Cancer
Drug: Avelumab
Drug: Pembrolizumab

This phase 3 study will be conducted in different countries all over the world.The purpose of this study is to compare how well Rina-S works against...

Active, not recruiting
Platinum-resistant Ovarian Cancer
Drug: Topotecan
Drug: Gemcitabine

The study will determine the recommended Phase 2 dose (RP2D) of livmoniplimab (ABBV-151) administered as monotherapy and in combination with budigali...

Active, not recruiting
Advanced Solid Tumors Cancer
Drug: Livmoniplimab
Drug: Budigalimab

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