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Indiana Hemophilia and Thrombosis Center | Indianapolis, IN

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Active trials

4 of 39 total trials

A Study to Evaluate the Efficacy and Safety of Factor IX Gene Therapy With PF-06838435 in Adult Males With Moderately Severe to Severe Hemophilia B (BENEGENE-2)

This study will evaluate the efficacy and safety of PF-06838435 (a gene therapy drug) in adult male participants with moderately severe to severe hem...

Active, not recruiting
Hemophilia B
Biological: PF-06838435/ fidanacogene elaparvovec

Participants in this study have a genetic mutation, specifically in the coagulation (blood clotting) Factor 9 gene that causes severe or moderately s...

Enrolling
Hemophilia B
Drug: LNP1265
Drug: REGV131

The objective of the study is to assess the improvement of synovial hypertrophy during the 12 months of efanesoctocog alfa prophylaxis once per week...

Enrolling
Factor VIII Deficiency
Drug: Efanesoctocog alfa

This is a phase II multicenter open-label, single-arm prospective study to evaluate the efficacy of prophylactic emicizumab administered on a schedul...

Active, not recruiting
Acquired Hemophilia A
Drug: emicizumab

Trial sponsors

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A
P
B
Daiichi Sankyo logo
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Regeneron Pharmaceuticals logo
Sanofi logo
Agios Pharmaceuticals logo
A

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