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Innovia Research Center | Miramar, FL

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ISIS 678354
Olezarsen
Bupropion Hydrochloride
Naltrexone Hydrochloride
SAR441566

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Active trials

4 of 4 total trials

A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia

The purpose of the study is to evaluate the efficacy of olezarsen as compared to placebo on the percent change in fasting triglycerides (TG) from bas...

Active, not recruiting
Severe Hypertriglyceridemia
Drug: Olezarsen
Drug: Placebo

This is a parallel group, Phase 2, randomized, double-blind, placebo controlled, 5-arm, international, multicenter, 12-week proof of concept, dose fi...

Enrolling
Rheumatoid Arthritis
Drug: SAR441566
Drug: Placebo

The purpose of this study is to evaluate the safety and tolerability of olezarsen in participants with SHTG.

Enrolling
Severe Hypertriglyceridemia
Drug: Olezarsen

A randomized, double-blinded, placebo controlled study intended to capture cardiovascular outcomes during real-world use of naltrexone/bupropion (NB).

Enrolling
Obesity
Drug: Placebo
Drug: Naltrexone-Bupropion (NB) Combination

Trial sponsors

Ionis Pharmaceuticals logo
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Sanofi logo

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