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Juno Research, Inc. | Southwest Site, Houston, TX

Research site
(Unclaimed)

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Top conditions

Top treatments

Metformin
Tirzepatide
LY3298176
LY3502970
Orforglipron
Retatrutide
Lorundrostat
Olezarsen
Dapagliflozin
LY3437943

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Active trials

29 of 79 total trials
Locations recently updated

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes (Enith2)

The purpose of this study is to assess the efficacy and safety of enicepatide, a dual glucagon-like peptide-1 (GLP-1)/glucose-dependent insulinotropi...

Enrolling
Obesity or Overweight
Type 2 Diabetes Mellitus
Combination Product: Enicepatide
Combination Product: Placebo

The main purpose of this study is to find out how well and how safely tirzepatide works long-term in adults who have type 1 diabetes and obesity or o...

Active, not recruiting
Overweight
Type 1 Diabetes
Drug: Placebo
Drug: Tirzepatide

This multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-range-finding, Phase II study aims to evaluate the efficacy, tol...

Active, not recruiting
Obesity or Overweight
Drug: RO7795081
Drug: Placebo

The main purpose of this study is to evaluate the efficacy and safety of eloralintide compared with placebo for body weight reduction in participants...

Enrolling
Overweight
Obesity
Drug: Eloralintide
Drug: Placebo

The main purpose of this study is to evaluate the efficacy and safety of eloralintide compared with placebo in participants with persistent obesity o...

Enrolling
Overweight
Obesity
Drug: Placebo
Drug: Eloralintide

This is a multi-center, randomized, double-blind, placebo-controlled, parallel group dose-finding study to evaluate the efficacy and safety of enicep...

Active, not recruiting
Type 2 Diabetes Mellitus (T2DM)
Overweight or Obese
Drug: Enicepatide
Drug: Placebo

The main purpose of this study is to learn more about the safety and efficacy of investigational tirzepatide doses in participants with Type 2 diabet...

Active, not recruiting
Obesity
Type 2 Diabetes
Drug: Tirzepatide
Drug: Placebo

The purpose of this study is to measure the change in hemoglobin A1c (HbA1c) with LY3457263 compared with placebo in participants with type 2 diabete...

Enrolling
Type 2 Diabetes
Drug: LY3457263
Drug: Placebo

The purpose of this study is to see how well LY3938577 works and how safe it is compared to degludec in people with type 2 diabetes. Participation in...

Enrolling
Diabetes Mellitus, Type 2
Drug: Degludec
Drug: LY3938577

This study will investigate the efficacy and safety of once daily oral orforglipron in adult participants with obesity or overweight with weight-rela...

Active, not recruiting
Overweight or Obesity
Overweight
Drug: Placebo
Drug: Orforglipron

The GZPT master protocol will support two independent studies, J2A-MC-GZT1 and J2A-MC-GZT2. Each study will see how well and safely orforglipron work...

Enrolling
Osteoarthritis
Drug: Orforglipron
Drug: Placebo

The purpose of this study is to evaluate the efficacy and safety of retatrutide in participants who have obesity or overweight (J1I-MC-GZBJ master pr...

Active, not recruiting
Overweight
Obesity
Drug: Retatrutide
Drug: Placebo

The main purpose of this study is to determine if combining tirzepatide with mibavademab will result in more weight loss in adult participants than t...

Active, not recruiting
Obesity
Drug: Mibavademab-Placebo
Drug: Tirzepatide-Placebo

The main aim of the study is to assess the effect of RO7204239 in combination with tirzepatide, compared to placebo in combination with tirzepatide,...

Active, not recruiting
Overweight
Obesity
Drug: Tirzepatide
Drug: RO7204239 Matching Placebo

This study will evaluate the efficacy and safety of Armour Thyroid treatment compared with synthetic T4 in subjects who have primary hypothyroidism a...

Enrolling
Hypothyroidism
Drug: Levothyroxine
Drug: Armour Thyroid

The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular risk in participants with high lipoprotein(a) who hav...

Active, not recruiting
Atherosclerotic Cardiovascular Disease (ASCVD)
Elevated Lp(a)
Drug: Lepodisiran Sodium
Drug: Placebo

The purpose of this study is to evaluate the safety and tolerability of olezarsen in participants with SHTG.

Active, not recruiting
Severe Hypertriglyceridemia
Drug: Olezarsen

The purpose of this study is to investigate the efficacy and safety of retatrutide compared with placebo in participants with Type 2 Diabetes and ren...

Active, not recruiting
Type 2 Diabetes
Drug: Retatrutide
Drug: Placebo

The purpose of this study is to investigate the efficacy and safety of retatrutide compared with semaglutide in participants with Type 2 Diabetes and...

Active, not recruiting
Diabetes Mellitus, Type 2
Drug: Retatrutide
Drug: Semaglutide

The primary objective of this study is to demonstrate that maridebart cafraglutide is superior to placebo for percent change in body weight.

Active, not recruiting
Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight
Drug: Maridebart cafraglutide
Drug: Placebo

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