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Keck School of Medicine of USC | Neurology Department

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Tacrolimus
Eptinezumab
Saline
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Ustekinumab
GLPG1690
Bromocriptine
Dextromethorphan
INS018_055
VY7523-102

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Active trials

12 of 40 total trials

A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES)

This study will determine the effect of oral 80 mg resmetirom administered once daily on participants with well-compensated non-alcoholic steatohepat...

Active, not recruiting
NASH
Cirrhosis, Liver
Drug: Resmetirom
Drug: Placebo

The purpose of this study is to learn about the effects of three study medicines (encorafenib, cetuximab, and pembrolizumab) given together for the t...

Active, not recruiting
Metastatic Colorectal Cancer
Biological: Pembrolizumab
Biological: Cetuximab

The purpose of the phase 1 part of this study is to evaluate how well pirtobrutinib is tolerated and what side effects may occur. The phase 2 part of...

Enrolling
Immune Thrombocytopenia (ITP)
Drug: Placebo
Drug: Pirtobrutinib

The purpose of this study is to demonstrate safety and effectiveness of the Biosense Webster (BWI) ablation system (THERMOCOOL SMARTTOUCH surround fl...

Active, not recruiting
Drug Refractory Paroxysmal Atrial Fibrillation
Device: THERMOCOOL STSF Bi- Directional Navigation Catheter
Device: TRUPULSE Generator
Locations recently updated

This is a multicenter, randomized, double-blind, placebo-controlled study that will evaluate the efficacy and safety of intravenous (IV) prasinezumab...

Active, not recruiting
Parkinsons Disease
Drug: Placebo
Drug: Prasinezumab

The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular risk in participants with high lipoprotein(a) who hav...

Enrolling
Atherosclerotic Cardiovascular Disease (ASCVD)
Elevated Lp(a)
Drug: Lepodisiran Sodium
Drug: Placebo

This study will evaluate the effect of adding abemaciclib to fulvestrant for the treatment of hormone receptor-positive (HR+), human epidermal growth...

Active, not recruiting
Breast Neoplasm
Neoplasm Metastasis
Drug: Fulvestrant
Drug: Placebo

This study will evaluate the long term safety and efficacy of AT-1501 (tegoprubart) compared with tacrolimus in patients undergoing kidney transplant...

Invitation-only
Kidney Transplant Rejection
Drug: AT-1501
Drug: Tacrolimus

The purpose of this revised Phase IIa study is to demonstrate safety of INS018\_055 over 12 weeks in adults with Idiopathic Pulmonary Fibrosis (IPF).

Enrolling
Idiopathic Pulmonary Fibrosis (IPF)
Drug: INS018_055
Drug: Placebo

The investigational drug to be studied in this protocol, BCA101, is a first-in-class compound that targets both EGFR with TGFβ. Based on preclinical...

Enrolling
Carcinoma, Squamous Cell
Cutaneous Squamous Cell Carcinoma
Drug: BCA101
Drug: Pembrolizumab

The objective of this prospective, randomized, blinded clinical trial is to assess the safety and efficacy of the Carillon Mitral Contour System in t...

Enrolling
Heart Valve Diseases
Mitral Valve Insufficiency
Other: Guideline Directed Heart Failure Medication
Device: Carillon Mitral Contour System

This study is to be conducted in participants with early Alzheimer's Disease to test VY7523, a new drug being researched for treatment of Alzheimer's...

Active, not recruiting
Alzheimer's Disease (AD)
Drug: Placebo Comparator
Drug: VY7523

Trial sponsors

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