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Kerwin Medical Center | Presbyterian Hospital Dallas

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LY3002813
Gantenerumab
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Active trials

13 of 23 total trials
Locations recently updated

A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease (TRONTIER 2)

The purpose of this study is to assess the efficacy and safety of trontinemab in participants with early symptomatic Alzheimer's disease (AD) (mild c...

Enrolling
Alzheimers Disease
Drug: Trontinemab
Other: Placebo

This study will investigate different donanemab dosing regimens and their effect on the frequency and severity of ARIA-E in adults with early symptom...

Active, not recruiting
Alzheimer's Disease
Mental Disorders
Drug: Dexamethasone
Drug: Placebo

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.Additional part...

Active, not recruiting
Alzheimer Disease
Drug: Donanemab
Drug: Placebo

The main purpose of this study is to evaluate whether treatment with donanemab slows the progression of cognitive (how we think, learn, remember, pay...

Not yet enrolling
Synucleinopathies
Amyloid
Drug: Donanemab
Drug: Placebo

The main purpose of this study is to look at how safe the study drug (mevidalen) is and whether it works to alleviate symptoms when given to people w...

Active, not recruiting
Alzheimer Disease
Drug: Placebo
Drug: Mevidalen

The purpose of this study is to measure the difference in time to developing or worsening memory, thinking, or functional problems due to Alzheimer's...

Active, not recruiting
Alzheimer's Disease
Drug: Placebo
Drug: Remternetug

The primary purpose of this study is to evaluate the efficacy of sabirnetug infusions administered once every four weeks (Q4W) in slowing cognitive a...

Active, not recruiting
Alzheimer Disease
Drug: Placebo
Drug: sabirnetug

Researchers want to learn if giving MK-1167 (the study medicine) along with acetylcholinesterase inhibitor (AChEI) therapy can improve symptoms of Al...

Active, not recruiting
Alzheimer Disease
Dementia
Drug: MK-1167
Drug: Placebo

The purpose of this study is to assess the efficacy of the oral medication IGC-AD1, a THC-based (Delta-9-Tetrahydrocannabinol) formulation administer...

Enrolling
NPS
Alzheimer Disease
Drug: IGC-AD1-Placebo
Drug: IGC-AD1-Active

The purpose of this study is to assess the safety, tolerability, biomarker, cognitive and clinical efficacy of investigational products in participan...

Active, not recruiting
Alzheimers Disease
Dementia
Drug: Solanezumab
Drug: E2814

This AR1001-ADP3-US01 protocol is a double-blind, randomized, placebo-controlled, multi- center, parallel-group comparison pivotal Phase 3 study to e...

Active, not recruiting
Alzheimer Disease
Drug: Placebo
Drug: AR1001

This Phase 1b study aims to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of multiple IV infusions...

Active, not recruiting
Alzheimer Disease, Early Onset
Drug: Placebo
Drug: PMN310

This study is a pre-screening process used to assess participants' potential eligibility for Roche interventional Alzheimer's disease studies.

Enrolling
Alzheimers Disease
Other: No Intervention

Trial sponsors

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