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Knowledge Research Center | Orange, CA

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BOS-580
Efimosfermin Alfa
BI 770371
Cilofexor
Firsocostat

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Active trials

4 of 12 total trials

A Study of BOS-580 in Obese Subjects at Risk for, or With Biopsy-confirmed, Nonalcoholic Steatohepatitis (NASH) With an Extension

This is a randomized, blinded, placebo-controlled study of Efimosfermin in obese participants at risk for, or with biopsy-confirmed, nonalcoholic ste...

Active, not recruiting
Nonalcoholic Steatohepatitis (NASH)
Drug: Placebo
Drug: Efimosfermin

The purpose of this study is to evaluate the safety, tolerability, preliminary efficacy, and pharmacokinetics (PK) of efimosfermin in participants wi...

Enrolling
Metabolic Dysfunction-Associated Steatohepatitis
Drug: Efimosfermin
Drug: Placebo
Locations recently updated

This study is open to people with cirrhosis caused by a liver disease called MASH (metabolic dysfunction-associated steatohepatitis). The purpose of...

Enrolling
Metabolic Dysfunction Associated Steatohepatitis (MASH)
Compensated Liver Cirrhosis
Drug: BI 770371
Drug: Placebo for BI 770371
Locations recently updated

This study is open to adults who are at least 18 years old and have:* A confirmed liver disease called non-alcoholic steatohepatitis (NASH) or* A con...

Enrolling
Metabolic Dysfunction Associated Steatohepatitis
Drug: Survodutide
Drug: Placebo matching survodutide

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