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Loma Linda University | Loma Linda University Medical Center - Diabetes Treatment Center

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Active trials

13 of 158 total trials

A Phase 3 Efficacy, Safety and Tolerability Study of Zolbetuximab (Experimental Drug) Plus mFOLFOX6 Chemotherapy Compared to Placebo Plus mFOLFOX6 as Treatment for Gastric and Gastroesophageal Junction (GEJ) Cancer (Spotlight)

A study of zolbetuximab (IMAB362) plus mFOLFOX6 versus placebo plus mFOLFOX6 in subjects with Claudin 18.2 positive, HER2-negative, locally advanced...

Active, not recruiting
Metastatic Gastric Adenocarcinoma or Cancer
Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer
Drug: fluorouracil
Drug: zolbetuximab
Locations recently updated

The objective of this randomized, surgically controlled, double-blinded, Phase 2 study is to evaluate the safety and efficacy of AAV2-GDNF delivered...

Enrolling
Parkinson Disease
Procedure: Control Surgery
Drug: AAV2-GDNF Gene therapy

The objective of this study is to compare standard negative pressure wound therapy with negative pressure wound therapy coupled with instillation for...

Enrolling
Ulcer
Wound
Device: Standard Negative Pressure Wound Therapy
Device: Negative pressure wound therapy coupled with instillation

This randomized trial will evaluate the effect of fenofibrate compared with placebo for prevention of diabetic retinopathy (DR) worsening through 6 y...

Enrolling
Diabetic Retinopathy
Other: Placebo
Drug: Fenofibrate

The purpose of this industry-initiated research study is to test that a powered microprocessor controlled knee improves metabolic function during wal...

Enrolling
Transfemoral Amputation
Other: Powered Microprocessor-controlled Knee (PMPK)

The objective of this study is to determine the safety and effectiveness of the smaller incision, new generation (SING), implantable miniature telesc...

Enrolling
Age-Related Macular Degeneration
Geographic Atrophy
Device: smaller incision, new generation implantable miniature telescope (SING-IMT)

This is a Phase 1b/2 study evaluating the anti-PD1 antibody, cemiplimab, in combination with either S095018 (anti-TIM3 antibody), S095024 (anti-CD73...

Enrolling
Non-small Cell Lung Cancer (NSCLC)
Drug: S095024 RDE
Drug: S095029 RDE

This is a prospective, open- label, single arm, multicenter clinical trial to evaluate the safety and effectiveness of the Cordella PA Sensor System...

Active, not recruiting
Heart Failure NYHA Class III
Device: Cordella™ Pulmonary Artery Sensor System

This is a prospective, multi-center, open label, randomized control clinical trial evaluating the safety and efficacy of the Cordella™ Pulmonary Arte...

Enrolling
Heart Failure NYHA Class II
Heart Failure NYHA Class III
Device: Cordella™ Pulmonary Artery Sensor System

Various patient groups with the On-X Valve can be maintained safely on lower doses of blood thinner(Coumadin®) or on antiplatelet drugs (aspirin/Plav...

Active, not recruiting
Heart Valve Disease
Device: On-X Valve with Standard warfarin Therapy
Device: On-X valve using reduced anticoagulation

Prospective, multi-center, randomized, single blind, controlled, noninferiority clinical trial.Subjects with previous bare-metal stent (BMS) or DES a...

Active, not recruiting
Coronary Restenosis
Device: SELUTION SLR™ DEB
Device: Control

Upper limb essential tremor (UL ET) is a movement disorder characterized by postural and/or kinetic tremor. It can cause difficulty with everyday tas...

Active, not recruiting
Upper Limb Essential Tremor (UL ET)
Drug: Placebo for BOTOX
Biological: BOTOX

This investigator-initiated, open-label, randomized controlled trial will explore the effects of two treatment arms, comparing standard treatment wit...

Enrolling
Cesarean Section Complications
Cesarean Section; Infection
Device: Irrisept
Drug: Normal Saline

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