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Loma Linda University | Loma Linda University Medical Center - Diabetes Treatment Center

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Active trials

12 of 162 total trials

A Study of AAV2-GDNF in Adults With Moderate Parkinson's Disease (REGENERATE-PD)

The objective of this randomized, surgically controlled, double-blinded, Phase 2 study is to evaluate the safety and efficacy of AAV2-GDNF delivered...

Enrolling
Parkinson Disease
Procedure: Control Surgery
Drug: AAV2-GDNF Gene therapy

Zolbetuximab is being studied in people with cancer in and around the stomach or where the food pipe (esophagus) joins the stomach, called gastroesop...

Active, not recruiting
Metastatic Gastric Adenocarcinoma or Cancer
Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer
Drug: folinic acid
Drug: zolbetuximab

This randomized trial will evaluate the effect of fenofibrate compared with placebo for prevention of diabetic retinopathy (DR) worsening through 6 y...

Enrolling
Diabetic Retinopathy
Other: Placebo
Drug: Fenofibrate

The purpose of this industry-initiated research study is to test that a powered microprocessor controlled knee improves metabolic function during wal...

Enrolling
Transfemoral Amputation
Other: Powered Microprocessor-controlled Knee (PMPK)

The objective of this study is to determine the safety and effectiveness of the smaller incision, new generation (SING), implantable miniature telesc...

Enrolling
Age-Related Macular Degeneration
Geographic Atrophy
Device: smaller incision, new generation implantable miniature telescope (SING-IMT)

This is a Phase 1b/2 study evaluating the anti-PD1 antibody, cemiplimab, in combination with either S095018 (anti-TIM3 antibody), S095024 (anti-CD73...

Enrolling
Non-small Cell Lung Cancer (NSCLC)
Drug: S095024 RDE
Drug: S095029 RDE

This is a prospective, open- label, single arm, multicenter clinical trial to evaluate the safety and effectiveness of the Cordella PA Sensor System...

Active, not recruiting
Heart Failure NYHA Class III
Device: Cordella™ Pulmonary Artery Sensor System

This is a prospective, multi-center, open label, randomized control clinical trial evaluating the safety and efficacy of the Cordella™ Pulmonary Arte...

Enrolling
Heart Failure NYHA Class II
Heart Failure NYHA Class III
Device: Cordella™ Pulmonary Artery Sensor System

The rollover study will provide ceritinib to patients who are currently receiving treatment with ceritinib within a Novartis-sponsored study and in t...

Active, not recruiting
ALK Positive Malignancies
Drug: ceritinib

Prospective, multi-center, randomized, single blind, controlled, noninferiority clinical trial.Subjects with previous bare-metal stent (BMS) or DES a...

Active, not recruiting
Coronary Restenosis
Device: SELUTION SLR™ DEB
Device: Control

The overall purpose of this two-part study is to evaluate the efficacy, safety and tolerability of iptacopan (LNP023) in addition to standard of care...

Enrolling
Lupus Nephritis
Drug: Iptacopan (part 2)
Drug: Iptacopan + placebo

This investigator-initiated, open-label, randomized controlled trial will explore the effects of two treatment arms, comparing standard treatment wit...

Enrolling
Cesarean Section Complications
Cesarean Section; Infection
Device: Irrisept
Drug: Normal Saline

Trial sponsors

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