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Lung Center of the Philippines | Pulmonary, Critical Care and Sleep Medicine Department

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MK-4482
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Active trials

5 of 22 total trials

Efficacy and Safety Evaluation of Two to Four Months of Treatment With the Combination Regimens of DBOS and PBOS in Adults With Pulmonary Tuberculosis

This multicenter, two-stage, open-label, randomized trial will aim to assess the efficacy, safety, optimal duration, and pharmacokinetics (PK) of Del...

Active, not recruiting
Pulmonary Tuberculosis
Drug: Isoniazid and Rifampicin (HR)
Drug: Isoniazid, Rifampicin, Pyrazinamide, Ethambutol (HRZE)

The main objective of the trial is to assess the efficacy and safety of trimodulin as adjunctive treatment to standard of care (SoC) compared to plac...

Enrolling
Community-acquired Pneumonia
Drug: Trimodulin
Drug: Placebo (human albumin 1%)

The purpose of this study is to evaluate the long-term safety and efficacy of pembrolizumab (MK-3475) in participants from previous Merck pembrolizum...

Enrolling
Solid Tumors
Hematologic Malignancies
Drug: Pembrolizumab
Drug: Lenvatinib

This study a randomized, double-blind, four arm study to evaluate the safety and efficacy of LYT-100 compared to pirfenidone or placebo in adults wit...

Active, not recruiting
Idiopathic Pulmonary Fibrosis
Drug: Deupirfenidone
Drug: Placebo

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (explores what the body does to the drug), and anti-mycobacterial...

Enrolling
Multidrug-Resistant Tuberculosis
Drug: Bedaquiline (TMC207)
Drug: Background Regimen (BR)

Trial sponsors

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