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Lung Center of the Philippines | Pulmonary, Critical Care and Sleep Medicine Department

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Active trials

5 of 20 total trials

Efficacy and Safety Evaluation of Two to Four Months of Treatment With the Combination Regimens of DBOS and PBOS in Adults With Pulmonary Tuberculosis

This multicenter, two-stage, open-label, randomized trial will aim to assess the efficacy, safety, optimal duration, and pharmacokinetics (PK) of Del...

Enrolling
Pulmonary Tuberculosis
Drug: Pretomanid, Bedaquiline, OPC-167832, and Sutezolid (PBOS)
Drug: Pretomanid or Delamanid, Bedaquiline, OPC-167832, and Sutezolid (XBOS)

The main objective of the trial is to assess the efficacy and safety of trimodulin as adjunctive treatment to standard of care (SoC) compared to plac...

Enrolling
Community-acquired Pneumonia
Drug: Trimodulin
Drug: Placebo (human albumin 1%)

The purpose of this study is to evaluate the long-term safety and efficacy of pembrolizumab (MK-3475) in participants from previous Merck pembrolizum...

Enrolling
Solid Tumors
Hematologic Malignancies
Drug: Pembrolizumab
Drug: Lenvatinib

This study a randomized, double-blind, four arm study to evaluate the safety and efficacy of LYT-100 compared to pirfenidone or placebo in adults wit...

Active, not recruiting
Idiopathic Pulmonary Fibrosis
Drug: Placebo
Drug: Deupirfenidone

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (explores what the body does to the drug), and anti-mycobacterial...

Enrolling
Multidrug-Resistant Tuberculosis
Drug: Bedaquiline (TMC207)
Drug: Background Regimen (BR)

Trial sponsors

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Boehringer Ingelheim logo
Janssen (J&J Innovative Medicine) logo
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Merck Sharp & Dohme (MSD) logo
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