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Luzerner Kantonsspital | Luzern - Cardiology Department

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Active trials

12 of 98 total trials

(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis

This is a randomized, double-blind, placebo-controlled, Phase 2/3 study comparing the efficacy and safety of elenestinib (BLU-263) + symptom directed...

Enrolling
Smoldering Systemic Mastocytosis
Indolent Systemic Mastocytosis
Drug: Placebo
Drug: Elenestinib

The purpose of this study is to evaluate the mavacamten impact on myocardial structure with cardiac magnetic resonance imaging (CMR) in adult partici...

Enrolling
Cardiomyopathy, Hypertrophic
Drug: Mavacamten
Locations recently updated

The purpose of this study is to compare the efficacy and safety of fixed duration pirtobruitinib (LOXO-305) with VR (Arm A) compared to VR alone (Arm...

Active, not recruiting
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Venetoclax
Drug: Rituximab

This study is a prospective, multicenter, randomized controlled trial of an interventional strategy using the ClotTriever System to achieve and maint...

Enrolling
Venous Thromboembolism
Deep Venous Thrombosis
Device: ClotTriever System
Drug: Commercially available/market approved anticoagulation medication including but not limited to: Heparin Sodium, Coumadin, Rivaroxaban, Apixaban, etc.

The purpose of this trial is to generate clinical evidence related to key performance outcomes of Endurant II/IIs Stent Graft Systems verses Gore Exc...

Enrolling
Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder)
Abdominal Aortic Aneurysm
Device: Gore Excluder or Gore/ Excluder Conformable AAA Endoprosthesis
Device: Medtronic Endurant II or Endurant IIs Stent Graft System

The aim of this study is to compare the efficacy of continuous ibrutinib monotherapy with fixed-duration venetoclax plus obinutuzumab and fixed-durat...

Active, not recruiting
Chronic Lymphoid Leukemia
Biological: Obinutuzumab
Biological: Venetoclax

The purpose of this study is to assess if using the Impella® CP (or Impella® 2.5) device during high-risk PCI in patients with reduced left-sided hea...

Enrolling
Coronary Artery Disease
Left Ventricular Dysfunction
Device: Impella CP® / Impella CP® with SmartAssist® / Impella 2.5®
Device: IABP Intra-aortic balloon pump

The purpose of this study is to evaluate the efficacy of addition of letrozole to the standard maintenance therapy in subjects following a primary di...

Enrolling
High-grade Serous Ovarian Carcinoma (HGSOC)
Fallopian Tube Neoplasms
Other: Placebo
Drug: Letrozole 2.5mg

POLAR is a phase III clinical trial, which will test the safety and efficacy of an investigational combination of drugs to learn whether the combinat...

Active, not recruiting
Breast Cancer Recurrent
Drug: Standard endocrine therapy
Drug: Palbociclib 125mg

This is a randomized open-label multicentre phase III superiority study of the effect of adding SABR to the standard of care treatment pembrolizumab...

Not yet enrolling
Oligometastatic Squamous Cell Carcinoma of the Head and Neck
Drug: Pembrolizumab
Radiation: stereotattic ablation radiotherapy (SABR)

Open label, real-world, prospective, multi-center, single arm, post-market surveillance study of the SELUTION SLR™ (Sustained Limus Release) drug elu...

Active, not recruiting
Peripheral Artery Disease
Device: SELUTION SLR™ (Sustained Limus Release) drug eluting balloon (DEB)

This study is a prospective, multicenter, randomized controlled trial of the FlowTriever System plus anticoagulation compared to anticoagulation alon...

Enrolling
Pulmonary Embolism
Drug: Anticoagulation Agents
Device: FlowTriever System

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