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Makati Medical Center | Clinical Research Center

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Active trials

10 of 29 total trials

A Global Phase III Clinical Trial of Recombinant COVID- 19 Vaccine (Sf9 Cells)

This Phase III study is a global multicenter, randomized, double-blind,placebo controlled clinical trial to evaluate the efficacy, safety, and immuno...

Active, not recruiting
COVID-19
Biological: Recombinant COVID-19 vaccine (Sf9 cells)
Other: Placebo control

This is a Phase 2/3 study that comprises 5 substudies designed to evaluate the efficacy, safety, and tolerability of oral etrasimod as therapy in adu...

Enrolling
Crohn's Disease
Drug: Placebo
Drug: Etrasimod

This is a Phase III, open-label, multicenter, randomized, two-arm study designed to evaluate the efficacy and safety of atezolizumab plus either lenv...

Active, not recruiting
Unresectable Hepatocellular Carcinoma
Drug: Lenvatinib
Drug: Atezolizumab

This is a prospective, multicenter, open-label, randomized, controlled, parallel Phase 3 study with an open-label single-arm extension period to eval...

Active, not recruiting
Pulmonary Arterial Hypertension
Drug: Macitentan
Other: Standard-of-care

This study is open to adults with schizophrenia. Schizophrenia can affect the way a person thinks, their memory and their mental functioning. Example...

Active, not recruiting
Schizophrenia
Drug: Iclepertin
Drug: Placebo

Phase 1, non-randomized, open label dose escalation clinical trial evaluating the safety of GEN2 in participants with primary \& metastatic liver tum...

Active, not recruiting
Metastatic Cancer
Hepatocellular Carcinoma
Drug: GEN2 (HSV-Thymidine Kinase-m2 and hGM-CSF Genes)

The drug that will be investigated in the study is an antibody, GEN3014. Since this is the first study of GEN3014 in humans, the main purpose is to e...

Enrolling
Acute Myeloid Leukemia (AML)
Relapsed or Refractory Multiple Myeloma (RRMM)
Biological: GEN3014
Drug: Daratumumab

A randomized, multi-center, double-blind, three arm placebo-controlled study in male and non-pregnant, non-lactating female subjects aged 18 years to...

Enrolling
Ulcerative Proctitis
Combination Product: Twice daily 90 mg hydrocortisone acetate suppository administered with Sephure applicator
Combination Product: Twice daily placebo suppository administered with Sephure applicator

The purpose of this study is to assess the efficacy and safety of platinum-based chemotherapy with or without INCMGA00012 in participants with metast...

Active, not recruiting
Metastatic Nonsquamous Non-Small Cell Lung Cancer
Metastatic Squamous Non-Small Cell Lung Cancer
Drug: nab-Paclitaxel
Drug: Paclitaxel

A Global, Multi-center, Randomized, Double-Blind, Placebo-Controlled, Phase III Clinical Study to Evaluate the Efficacy, Safety, and Immunogenicity o...

Active, not recruiting
COVID-19 Pandemic
Biological: Recombinant SARS-CoV-2 fusion protein vaccine (V-01)
Other: Blank Preparation of Recombinant SARS-CoV-2 Fusion Protein Vaccine (V-01)

Trial sponsors

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