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Makati Medical Center | Clinical Research Center

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Active trials

8 of 30 total trials

A Global Phase III Clinical Trial of Recombinant COVID- 19 Vaccine (Sf9 Cells)

This Phase III study is a global multicenter, randomized, double-blind,placebo controlled clinical trial to evaluate the efficacy, safety, and immuno...

Active, not recruiting
COVID-19
Other: Placebo control
Biological: Recombinant COVID-19 vaccine (Sf9 cells)

This is a Phase 2/3 study that comprises 5 substudies designed to evaluate the efficacy, safety, and tolerability of oral etrasimod as therapy in adu...

Enrolling
Crohn's Disease
Drug: Placebo
Drug: Etrasimod

This is a Phase III, open-label, multicenter, randomized, two-arm study designed to evaluate the efficacy and safety of atezolizumab plus either lenv...

Active, not recruiting
Unresectable Hepatocellular Carcinoma
Drug: Lenvatinib
Drug: Atezolizumab

This is a prospective, multicenter, open-label, randomized, controlled, parallel Phase 3 study with an open-label single-arm extension period to eval...

Active, not recruiting
Pulmonary Arterial Hypertension
Drug: Macitentan
Other: Standard-of-care

Phase 1, non-randomized, open label dose escalation clinical trial evaluating the safety of GEN2 in participants with primary \& metastatic liver tum...

Active, not recruiting
Metastatic Cancer
Hepatocellular Carcinoma
Drug: GEN2 (HSV-Thymidine Kinase-m2 and hGM-CSF Genes)

The drug that will be investigated in the study is an antibody, GEN3014. Since this is the first study of GEN3014 in humans, the main purpose is to e...

Enrolling
Acute Myeloid Leukemia (AML)
Relapsed or Refractory Multiple Myeloma (RRMM)
Biological: GEN3014
Drug: Daratumumab

The purpose of this study is to assess the efficacy and safety of platinum-based chemotherapy with or without INCMGA00012 in participants with metast...

Active, not recruiting
Metastatic Nonsquamous Non-Small Cell Lung Cancer
Metastatic Squamous Non-Small Cell Lung Cancer
Drug: Placebo
Drug: Paclitaxel

A Global, Multi-center, Randomized, Double-Blind, Placebo-Controlled, Phase III Clinical Study to Evaluate the Efficacy, Safety, and Immunogenicity o...

Active, not recruiting
COVID-19 Pandemic
Biological: Recombinant SARS-CoV-2 fusion protein vaccine (V-01)
Other: Blank Preparation of Recombinant SARS-CoV-2 Fusion Protein Vaccine (V-01)

Trial sponsors

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