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Manhattan Medical Research | New York, NY

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Elagolix
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Active trials

9 of 42 total trials

A Phase 1 Dose-escalation Study of UGN-301 in Patients With Recurrent Non-muscle Invasive Bladder Cancer (NMIBC)

This study is being conducted to evaluate the safety and determine the recommended Phase 2 dose (RP2D) of UGN-301 (zalifrelimab) administered intrave...

Enrolling
Carcinoma in Situ of Bladder
Non-muscle Invasive Bladder Cancer
Drug: UGN-201
Drug: Gemcitabine

This Phase 3, multinational, single-arm, multicenter study will evaluate the efficacy and safety of UGN-102 as primary chemoablative therapy in patie...

Active, not recruiting
Bladder Cancer
Urothelial Carcinoma
Drug: UGN-102

This is a Phase Ib/IIb, randomized, two-cohort, open-label, multicenter study of intravesical N-803 plus BCG versus BCG alone, in BCG naïve patients...

Enrolling
Non-muscle Invasive Bladder Cancer
Biological: BCG( 50mg/Instillation)
Biological: BCG+N-803( 50mg BCG/ Instillation+ N-803( 400 μg/instillation). )

The purpose of this study is to demonstrate the efficacy of 9-valent extraintestinal pathogenic Escherichia coli vaccine (ExPEC9V) compared to placeb...

Enrolling
Invasive Extraintestinal Pathogenic Escherichia Coli Disease (IED) Prevention
Biological: ExPEC9V
Other: Placebo

The study was performed to assess the efficacy and safety of Vilaprisan in subjects with uterine fibroids compared to standard of care

Active, not recruiting
Uterine Fibroids
Drug: Vilaprisan (BAY1002670)
Other: Standard of care

A prospective, multicenter, blind randomized (2:1) controlled study comparing the International Prostate Symptom Score (IPSS) of the Active arm to th...

Enrolling
BPH (Benign Prostatic Hyperplasia)
Lower Urinary Tract Symptoms (LUTS)
Device: Butterfly Prostatic Retraction Device

A multi-center, randomized, double-blind, placebo-controlled study to investigate the efficacy of tradipitant in participants affected by motion sick...

Enrolling
Motion Sickness
Drug: Placebo
Drug: Tradipitant

This trial is a prospective, multicenter, single-arm study of the safety and effectiveness of eCoinTM tibial nerve stimulation in subjects having ove...

Active, not recruiting
Urinary Urge Incontinence
Incontinence, Urinary
Device: eCoin Tibial Nerve Stimulation

This is a Phase II/III, open-label, single-arm, multicenter study of intravesical BCG plus N-803 or N-803 only in patients with BCG unresponsive high...

Active, not recruiting
Bladder Cancer
Drug: N-803
Drug: N-803 and BCG

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