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Maple Leaf Research | Toronto, Canada

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Emtricitabine
Tenofovir Alafenamide
TDF
Doravirine
Islatravir
Rilpivirine
TAF
ISL
LY3841136
Tenofovir Disoproxil Fumarate

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Active trials

9 of 25 total trials

A Study of Doravirine/Islatravir (DOR/ISL, MK-8591A) for the Treatment of Human Immunodeficiency Virus 1 (HIV-1) Infection in Participants Who Previously Received DOR/ISL (MK-8591A-054)

The purpose of this study is to evaluate the safety and tolerability of DOR/ISL in adult participants with HIV-1 who had been previously treated with...

Active, not recruiting
HIV Infection
Drug: DOR/ISL
Recently updated

The purpose of the studies is to evaluate the efficacy and safety of eloralintide in participants with moderate-to-severe obstructive sleep apnea and...

Begins enrollment this month
Overweight
Sleep Apnea, Obstructive
Drug: Placebo
Drug: Eloralintide

The purpose of this study is to measure the change in hemoglobin A1c (HbA1c) with LY3457263 compared with placebo in participants with type 2 diabete...

Enrolling
Type 2 Diabetes
Drug: LY3457263
Drug: Placebo

This is a study of retatrutide in participants with obesity. The main purpose is to learn more about how retatrutide maintains body weight loss. The...

Active, not recruiting
Obesity
Drug: Retatrutide
Drug: Placebo

The primary objectives of this study are to evaluate the safety and tolerability of a switch to Doravirine/Islatravir (DOR/ISL) compared with continu...

Active, not recruiting
HIV-1 Infection
Drug: DOR/ISL
Drug: ART

The purpose of this study is to investigate the efficacy and safety of retatrutide compared with semaglutide in participants with Type 2 Diabetes and...

Active, not recruiting
Diabetes Mellitus, Type 2
Drug: Retatrutide
Drug: Semaglutide

The YDAN master protocol will support two independent studies, J3R-MC-YOA1 and J3R-MC-YOA2. Each study will investigate how well and safely Eloralint...

Not yet enrolling
Overweight or Obesity
Osteoarthritis
Drug: Placebo
Drug: Eloralintide

The safety and tolerability of MK-8591A, a 2-drug fixed dose combination (FDC) of doravirine (100mg) and islatravir (0.75mg) \[DOR/ISL 100 mg/0.75 mg...

Active, not recruiting
HIV-1 Infection
Drug: MK-8591A

The goal of this clinical study is to learn more about the effects of switching to the study drugs, bictegravir (BIC) plus lenacapavir (LEN), versus...

Active, not recruiting
HIV-1-infection
Drug: Stable Baseline Regimen
Drug: Bictegravir

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