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Medicines Evaluation Unit | Manchester, England

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Active trials

5 of 70 total trials

A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPD

The purpose of this study is to assess the efficacy and safety of verekitug (UPB-101) in participants with moderate-to-severe Chronic Obstructive Pul...

Active, not recruiting
Chronic Obstructive Pulmonary Disease
Other: Placebo
Drug: Verekitug

This study is testing the safety, tolerability, pharmacokinetics and pharmacodynamics of GB-0895.

Active, not recruiting
Asthma
COPD (Chronic Obstructive Pulmonary Disease)
Biological: GB-0895 (SC)
Drug: Placebo (SC)

This is a phase 2b, randomized, double-blind, placebo-controlled, dose-ranging,14-day dosing, 2-period crossover study in participants with chronic o...

Enrolling
Lung Diseases, Obstructive
Lung Disease Chronic
Drug: AERO-002
Drug: AERO-001

Nested Phase 1-2 Trial of RIG-101 in Healthy and Asthmatic Participants Assessing Safety, Tolerability and Viral Challenge Efficacy

Enrolling
Healthy Adult Participants
Asthma Exacerbation
Drug: RIG-101
Other: Placebo

This study will compare an asthma inhaler that uses a new climate friendly alternative propellant to an asthma inhaler with an existing propellant. W...

Enrolling
Asthma
Drug: CHF5993 pMDI with HFA-134a
Drug: CHF5993 pMDI with HFA-152a

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