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Michigan State University | Department of Neurology

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Active trials

8 of 210 total trials

A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors That Cannot be Removed by Surgery

This phase II trial studies the side effects and how well nirogacestat works in treating patients less than 18 years of age with desmoid tumors that...

Active, not recruiting
Desmoid Fibromatosis
Unresectable Desmoid Fibromatosis
Drug: Nirogacestat
Procedure: Echocardiography Test

The objective of this randomized, surgically controlled, double-blinded, Phase 2 study is to evaluate the safety and efficacy of AAV2-GDNF delivered...

Enrolling
Parkinson Disease
Drug: AAV2-GDNF gene therapy
Procedure: control surgery

The purpose of this study is to evaluate whether milvexian compared to placebo reduce the risk of recurrent ischemic stroke.

Enrolling
Ischemic Stroke; Ischemic Attack, Transient
Drug: Placebo
Drug: Milvexian

This study will evaluate the long term safety, tolerability, pharmacokinetics (PK), and efficacy of XEN1101 in subjects with Focal Onset Seizures (FO...

Invitation-only
Tonic-Clonic Seizures
Focal Epilepsy
Drug: XEN1101

The main purpose of this study is to learn if the usual chemotherapy given before surgery (neoadjuvant therapy) for breast cancer plus the experiment...

Active, not recruiting
Triple Negative Breast Cancer
Drug: Atezolizumab
Drug: Placebo

This is a multi-center, randomized, double-blind, double-dummy, active controlled clinical Study. Following a screening period, eligible subjects wil...

Active, not recruiting
Parkinson's Disease
Drug: Placebo for Oral IR-LD/CD
Drug: Oral IR-LD/CD

The primary objective is to understand the utility of Personal KinetiGraph movement recording system data in the clinical management of Parkinson's d...

Active, not recruiting
Parkinson Disease
Device: Personal KinetiGraph™ (PKG™)

This is a Phase 3, multicenter, randomized, double-blind, safety and efficacy study of contezolid acefosamil (IV)/contezolid (PO) compared with linez...

Enrolling
Diabetic Foot Infection
Drug: contezolid acefosamil (IV)/contezolid (PO)
Drug: Linezolid (IV and PO)

Trial sponsors

Michigan State University logo
C
National Cancer Institute (NCI) logo
N
B
Baxalta logo
Pfizer logo
Janssen (J&J Innovative Medicine) logo
Novo Nordisk logo
A

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