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Active trials

7 of 21 total trials

A Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Crohn's Disease Who Completed the Studies M14-431 or M14-433 (U-ENDURE)

A multicenter study to evaluate the efficacy and safety of maintenance and long-term treatment administration of upadacitinib, an orally administered...

Active, not recruiting
Crohn's Disease
Drug: Placebo for Upadacitinib
Drug: Upadacitinib
Locations recently updated

The purpose of this study is to assess how well guselkumab works when compared to risankizumab in participants with moderately to severely active Cro...

Enrolling
Crohn Disease
Drug: Guselkumab
Drug: Risankizumab

Ulcerative Colitis (UC) and Crohn's Disease (CD) are long-term conditions in the gut that can cause diarrhea, swelling (inflammation), bleeding from...

Enrolling
Ulcerative Colitis
Crohn's Disease
Drug: Vedolizumab SC
Drug: Vedolizumab IV

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large...

Active, not recruiting
Ulcerative Colitis
Drug: Risankizumab
Drug: Vedolizumab

This study is designed to evaluate the long-term safety and efficacy of Upadacitinib in participants with ulcerative colitis (UC) who have not respon...

Active, not recruiting
Ulcerative Colitis (UC)
Drug: Placebo
Drug: Upadacitinib (ABT-494)

The main aim is to see how DONQ52 works to improve small intestinal damage and reduce celiac-related symptoms due to gluten exposure, in participants...

Enrolling
Celiac Disease
Dietary Supplement: Simulated Inadvertent Gluten Exposure (SIGE) capsule
Drug: DONQ52

Crohn's disease (CD) is a long-lasting disease that causes severe inflammation (redness, swelling), in the digestive tract, most frequently affecting...

Enrolling
Crohn's Disease
Drug: Risankizumab
Drug: Trosunilimab

Trial sponsors

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