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Neuro-Behavioral Clinical Research | North Canton, OH

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Top conditions

Top treatments

KarXT
Simufilam
SEP-363856
MK-2214
SEP-4199
Etavopivat
BI 1569912
fezolinetant
TRx0237
venlafaxine XR

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Active trials

10 of 44 total trials

A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

Researchers want to know if the study treatment called MK-2214 works to slow certain changes in the brains of people with Alzheimer's disease (AD). A...

Enrolling
Early Alzheimer's Disease
Biological: MK-2214
Drug: Placebo

A Phase 3, Double-blind, Placebo-controlled Study (Part A) with an Open-label Extension (Part B) Evaluating MM120 Compared to Placebo in Generalized...

Enrolling
Generalized Anxiety Disorder
Drug: MM120 (LSD D-Tartrate)
Other: Placebo

Etavopivat is a new medicine under development for treating blood disorders like sickle cell disease and thalassaemia. Sickle cell disease and thalas...

Enrolling
Thalassemia
Sickle Cell Disease
Drug: Etavopivat C
Drug: Etavopivat B

This clinical trial is a Phase 2/3 study that will evaluate the efficacy and safety of etavopivat and test how well etavopivat works compared to plac...

Active, not recruiting
Sickle Cell Disease
Drug: Placebo Tablets
Drug: Etavopivat Tablets High dose

This is a phase 3, open-label extension study to assess the long-term safety of KarXT for the treatment of mania or mania with mixed features in Bipo...

Enrolling
Bipolar Disorder Type I With Mania
Drug: Valproate
Drug: Lamotrigine

This is a Phase 2, randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety, Pharmacokinetic (PK) and Pharmacodynamic (PD)...

Enrolling
Cognitive Impairment Associated With Schizophrenia (CIAS)
Other: Placebo
Drug: KYN-5356 low dose

The purpose of this study is to evaluate the efficacy and safety of KarXT for the treatment of manic episodes in Bipolar-I Disorder

Enrolling
Bipolar-I Disorder With Mania or Mania With Mixed Features
Drug: KarXT
Other: Placebo

This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter, inpatient study in participants with bipolar disorder experiencing an a...

Enrolling
Bipolar Disorder Type I With Mania or Mania With Mixed Features
Drug: KarXT
Other: Placebo

This is a randomized, double-blind, placebo-controlled, multiple-dose study of ALA-3000 designed to evaluate the safety, tolerability, pharmacokineti...

Active, not recruiting
Treatment Resistant Depression
Drug: ALA-3000
Drug: escitalopram, sertraline, duloxetine or venlafaxine XR

The purpose of this study is to test the safety and efficacy of BHV-3000 versus placebo in the acute treatment of moderate or severe migraine in chil...

Enrolling
Pediatric Migraine
Drug: Rimegepant/BHV3000
Drug: Matching placebo

Trial sponsors

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