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Neurology Rare Disease Center | Denton, TX

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Top conditions

Top treatments

EDG-5506
NMD670
Risdiplam
AOC 1044
Taldefgrobep Alfa

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Active trials

8 of 10 total trials

A Study of Efgartigimod PH20 SC in Children Between 2 and Less Than 18 Years of Age with Generalized Myasthenia Gravis (ADAPT Jr SC)

The purpose of this study is to measure the pharmacokinetics (PK), pharmacodynamics (PD), safety, tolerability, and immunogenicity of efgartigimod PH...

Enrolling
Generalized Myasthenia Gravis
Biological: Efgartigimod PH20 SC

The primary objective of this study is to evaluate motor function following treatment with HD nusinersen in participants with spinal muscular atrophy...

Enrolling
Spinal Muscular Atrophy
Drug: Nusinersen

This trial will study the efficacy and safety of taldefgrobep alfa as an adjunctive therapy for participants who are already taking a stable dose of...

Active, not recruiting
Neuromuscular Diseases
SMA
Drug: Placebo
Drug: taldefgrobep alfa

EDG-5506-203 MESA is an open-label extension study to assess the long-term effect of sevasemten (EDG-5506) on safety, biomarkers, and functional meas...

Invitation-only
Becker Muscular Dystrophy
Drug: Sevasemten

AOC 1044-CS2 (EXPLORE44-OLE) is an Open-label Study to Evaluate the Pharmacodynamics and Long-Term Safety and Tolerability of AOC 1044 Administered I...

Enrolling
Exon 44
DMD
Drug: AOC 1044

A study of sevasemten (EDG-5506) in Becker muscular dystrophy (known as CANYON) and pivotal cohort (known as GRAND CANYON). The EDG-5506-201 CANYON s...

Enrolling
Becker Muscular Dystrophy
Drug: Placebo
Drug: Sevasemten 10 mg

The purpose of this study is to evaluate the efficacy, safety, tolerability and pharmacokinetics of NMD670 in the treatment of ambulatory adults with...

Enrolling
Spinal Muscular Atrophy
Drug: Placebo
Drug: NMD670

A randomized, open-label, prospective, multicenter study designed to investigate 2 dose levels in pediatric subjects 2 to ≤ 17 years of age with conf...

Enrolling
Pediatric Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Biological: IgPro10

Trial sponsors

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