New England Cancer Specialists | Scarborough, ME

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100 Campus Drive Suite 108, Scarborough, Maine, United States of America

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Active trials

15 of 16 total trials

A Phase III, Open-Label Study of Maintenance Lurbinectedin in Combination With Atezolizumab Compared With Atezolizumab in Participants With Extensive-Stage Small-Cell Lung Cancer (IMforte)

Study GO43104 is a Phase III, randomized, open-label, multicenter study of lurbinectedin in combination with atezolizumab compared with atezolizumab...

Active, not recruiting
Small-Cell Lung Cancer
Drug: Atezolizumab
Drug: Lurbinectedin
Recently updated

This is a global, multicenter, open-label safety extension study. Participants receiving single-agent trastuzumab emtansine or trastuzumab emtansine...

Neoplasm Metastasis
Drug: Trastuzumab
Drug: Pertuzumab

This is a Phase III, two-arm, randomized, double-blind placebo-controlled study in participants with HER2-positive primary breast cancer who have rec...

Breast Cancer
Drug: Trastuzumab Emtansine
Drug: Placebo

This Phase III, randomized, open-label, multicenter study will evaluate the efficacy and safety of giredestrant plus everolimus compared with the phy...

Estrogen Receptor (ER)-Positive, HER2-negative, Locally Advanced or Metastatic Breast Cancer
Drug: Fulvestrant
Drug: Dexamethasone Mouth Rinse

This is an open-label, multicenter, non-randomized extension and long-term observational study. Participants receiving atezolizumab monotherapy or at...

Active, not recruiting
Drug: Atezolizumab
Drug: Bevacizumab
Locations recently updated

This is an open-label, multicenter, extension study. Patients who are receiving clinical benefit from atezolizumab monotherapy or atezolizumab in com...

Drug: Emactuzumab
Drug: Niraparib

This 2-arm, randomized, open-label study will evaluate the efficacy and safety of trastuzumab emtansine versus trastuzumab as adjuvant therapy in pat...

Active, not recruiting
Breast Cancer
Drug: trastuzumab
Drug: trastuzumab emtansine

This is a Phase III, randomized, open-label multicenter study that will evaluate the efficacy and safety of giredestrant compared with fulvestrant, b...

Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer
Diagnostic Test: FoundationOne Liquid CDx Assay (F1LCDx)
Drug: Giredestrant
Locations recently updated

This research study is studying how well newly diagnosed breast cancer that has tested positive for a protein called HER2 responds using one of two d...

Breast Cancer
HER2-positive Breast Cancer
Drug: Paclitaxel
Drug: trastuzumab-emtansine

This is a study of perioperative pembrolizumab or enfortumab vedotin in combination with pembrolizumab in participants who are cisplatin-ineligible o...

Active, not recruiting
Urinary Bladder Cancer, Muscle-invasive
Procedure: Surgery (radical cystectomy (RC) plus Pelvic Lymph Node Dissection [PLND])
Drug: Pembrolizumab
Locations recently updated

A Randomized, Double-blind, Multi-center, Phase III Clinical Study of AK112 or Placebo Combined With Pemetrexed and Carboplatin in Patients With EGFR...

Non-Squamous Non-small Cell Lung Cancer
Drug: Placebo Injection
Drug: AK112 Injection

The primary hypothesis is that pembrolizumab/vibostolimab (MK-7684A) in combination with chemotherapy is superior to pembrolizumab in combination wit...

Active, not recruiting
Metastatic Non-Small Cell Lung Cancer
Biological: Pembrolizumab
Drug: Cisplatin

The goal of this study is to find out if the experimental product, sacituzumab govitecan-hziy (SG) in combination with pembrolizumab given after surg...

Triple Negative Breast Cancer
Drug: Capecitabine
Drug: Sacituzumab govitecan-hziy (SG)

This is a Phase III, global, multicenter, open-label, randomized study to compare the efficacy and safety of 16 cycles (1 cycle duration=21 days) of...

Active, not recruiting
Non-Small Cell Lung Cancer
Drug: Gemcitabine
Drug: Pemetrexed

TAPISTRY is a Phase II, global, multicenter, open-label, multi-cohort study designed to evaluate the safety and efficacy of targeted therapies or imm...

Solid Tumors
Drug: Atezolizumab
Drug: Trastuzumab emtansine

Trial sponsors

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Genentech logo
Merck Sharp & Dohme (MSD) logo
Dana-Farber Cancer Institute logo
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Stemline Therapeutics logo
Summit Therapeutics logo

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