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North Carolina Retina Associates | Wake Forest

Research site
(Unclaimed)

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Top conditions

Top treatments

Aflibercept
KSI-101
EYP-1901
OCS-01
MK-8748-004
CT1812
BI 1815368
Tarcocimab
ANX007
AVD-104

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Active trials

13 of 20 total trials

A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUCIA) Primary Efficacy Will be Determined at Week 56

This is a phase 3 randomized, double -masked study comparing the efficacy of EYP-1901 against Aflibercept.

Active, not recruiting
Wet Age Related Macular Degeneration
wAMD
Drug: Aflibercept (2.0 mg)
Drug: EYP-1901
Locations recently updated

Researchers are looking for new ways to treat diabetic macular edema (DME). In this trial, researchers want to learn if a trial medicine called MK-87...

Enrolling
Macular Edema
Diabetic Retinopathy
Drug: MK-8748
Drug: Aflibercept

A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants with Macular Edema Secondary to Inflammation (MESI)

Enrolling
Macular Edema Secondary to Inflammation
Other: Sham Comparator
Drug: KSI-101

A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants with Macular Edema Secondary to Inflammation (MESI)

Enrolling
Macular Edema Secondary to Inflammation
Drug: KSI-101
Other: Sham Comparator

This study is researching aflibercept high dose (HD), referred to as "study drug", with an experimental dosing regimen. The study is focused on parti...

Active, not recruiting
Neovascular Age-Related Macular Degeneration
Diabetic Macular Edema
Drug: Aflibercept 8 mg

This study is open to adults with diabetic macular edema that involves the center of the eye. The purpose of this study is to find out how well diffe...

Enrolling
Diabetic Macular Edema
Biological: High dose BI 3812465
Biological: Low dose BI 3812465

This study is researching experimental (study) drugs called pozelimab and cemdisiran. The study is focused on participants who have Geographic Atroph...

Enrolling
Age-related Macular Degeneration (AMD)
Geographic Atrophy (GA)
Drug: Placebo
Drug: Pozelimab

The primary purpose of the study is to determine if IVT injections of vonaprument every month reduce vision loss in participants with dry AMD with GA.

Active, not recruiting
Geographic Atrophy
Drug: Vonaprument
Other: Sham Administration

A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants with Neovascular (...

Active, not recruiting
Wet Age-related Macular Degeneration
Drug: Tarcocimab tedromer
Drug: Aflibercept
Locations recently updated

This study is open to adults 18 and older with an eye condition called diabetic macular edema. People are required to have a specific type of diabeti...

Enrolling
Macular Edema
Drug: BI 1815368
Drug: Placebo

This is a phase 3 randomized, double -masked study comparing the efficacy of EYP-1901 against Aflibercept.

Active, not recruiting
Diabetic Macular Edema (DME)
Diabetic Macular Edema
Drug: Aflibercept (2.0 mg)
Drug: EYP-1901

OPL-0401-201 is a multicenter study to investigate the safety and efficacy of OPL-0401 in patients with diabetes mellitus (DM) with diabetic retinopa...

Active, not recruiting
Non-proliferative Diabetic Retinopathy
Proliferative Diabetic Retinopathy
Drug: Placebo
Drug: OPL-0401 Dose 1

A Phase 3, Randomized, Double-Masked, Active-Controlled Trial in Adults with Macular Neovascularization Secondary to Age-Related Macular Degeneration

Enrolling
Neovascular Age-Related Macular Degeneration (nAMD)
Biological: 4D-150 IVT (3E10 vg/eye)
Biological: EYLEA® (aflibercept) Injection 2 mg (0.05mL)

Trial sponsors

Kodiak Sciences logo
Boehringer Ingelheim logo
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Regeneron Pharmaceuticals logo
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Astellas logo
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Cognition Therapeutics logo
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