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Northeast Clinical Research Center | Bethlehem, PA

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Top treatments

Lixivaptan
Bardoxolone Methyl
Pegcetacoplan
BI 764198
Selonsertib
BION-1301
UDCA
Iron
Sirolimus
Sofosbuvir

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Active trials

13 of 46 total trials

A Study of Acthar Gel Alone or With Tacrolimus to Reduce Proteinuria in Fibrillary Glomerulopathy Patients (FACT)

A Multicenter, Comparative Safety and Efficacy Study of Acthar gel alone or in combination with oral Tacrolimus to reduce urinary proteinuria in pati...

Active, not recruiting
Fibrillary Glomerulonephritis
Drug: Acthar Gel 80 UNT/ML Injectable Solution

Safety and Efficacy of BION-1301 in Adults with IgA Nephropathy

Active, not recruiting
Immunoglobulin A Nephropathy
IgA Nephropathy
Drug: Placebo
Drug: BION-1301
Locations recently updated

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common genetic cause of kidney disease that causes fluid-filled cysts to develop in...

Enrolling
Autosomal Dominant Polycystic Kidney Disease
Drug: ABBV-CLS-628
Drug: Placebo
Locations recently updated

This study is open to adults and adolescents with a kidney condition called focal segmental glomerulosclerosis (FSGS). The purpose of this study is t...

Not yet enrolling
Focal Segmental Glomerulosclerosis
Drug: Placebo
Drug: BI 764198

Researchers are looking for a better way to treat people who have non-diabetic chronic kidney disease (non-diabetic CKD). The trial treatment, finere...

Active, not recruiting
Non-diabetic Chronic Kidney Disease
Drug: Finerenone (BAY94-8862)
Drug: Placebo

This study is designed as a long-term extension to Study APL2-C3G-310, and is being conducted to establish the long-term safety and efficacy of pegce...

Active, not recruiting
Membranoproliferative Glomerulonephritis (MPGN)
Membranoproliferative Glomerulonephritis
Drug: Pegcetacoplan
Locations recently updated

This study is open to adults with certain kidney conditions, including secondary focal segmental glomerulosclerosis (sFSGS), treatment-resistant prim...

Begins enrollment this month
Proteinuric Kidney Diseases
Drug: Placebo matching BI 764198
Drug: BI 764198

This study is an open-label, multi-center study evaluating the clinical utility of Renasight in the diagnosis and management of kidney disease.

Active, not recruiting
Kidney Diseases
Diagnostic Test: Renasight

Multicenter study designed to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of BION-1301 in healthy volunteers...

Active, not recruiting
IgA Nephropathy
Drug: BION-1301 Multiple Doses
Drug: Placebo Multiple Doses

An Open Label Long-Term Study to Evaluate the Safety and Tolerability of Seladelpar in Subjects with Primary Biliary Cholangitis (PBC)

Active, not recruiting
Primary Biliary Cirrhosis
Drug: Seladelpar 5 mg Capsule
Drug: Seladelpar 10 mg Capsule
Status recently updated

This study is researching experimental drugs called ALN-ANG3 and evinacumab (called "study drugs"). The study is focused on participants who have dia...

Not yet enrolling
Enrolling
Diabetic Kidney Disease (DKD)
Drug: Evinacumab
Drug: ALN-ANG3 placebo

The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications or prevent...

Enrolling
Atherosclerotic Cardiovascular Disease (ASCVD)
Chronic Kidney Disease (CKD)
Drug: Retatrutide
Drug: Placebo

This study is conducted to see if ziltivekimab reduces the risk of having cardiovascular events (for example heart attack and stroke) in people with...

Active, not recruiting
Chronic Kidney Disease
Inflammation
Drug: Placebo (Ziltivekimab B)
Drug: Placebo (Ziltivekimab C)

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