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Active trials

8 of 77 total trials

A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia

The purpose of the study is to evaluate the effect of olezarsen on percent change in fasting triglyceride (TG) levels compared to placebo in particip...

Active, not recruiting
Hypertriglyceridemia
Cardiovascular Diseases
Drug: Placebo
Drug: Olezarsen

The purpose of this study is to demonstrate the efficacy of 9-valent extraintestinal pathogenic Escherichia coli vaccine (ExPEC9V) compared to placeb...

Enrolling
Invasive Extraintestinal Pathogenic Escherichia Coli Disease (IED) Prevention
Biological: ExPEC9V
Other: Placebo

The main purpose of this study is to evaluate the efficacy of mRNA 1647 vaccine in CMV-seronegative female participants and to evaluate the safety an...

Active, not recruiting
Cytomegalovirus Infection
Biological: mRNA-1647
Biological: Placebo

Trial Title A randomized, double blind sham controlled clinical trial to evaluate the efficacy of vestibular nerve stimulation (VeNS), together with...

Active, not recruiting
Type 2 Diabetes
Device: Vestal DM Active device
Behavioral: Lifestyle modification

This is a Pre-IDE, prospective, multicenter, randomized, parallel-group, double-blind, vehicle- controlled study to evaluate safety and effectiveness...

Enrolling
Distal Lateral Subungual Onychomycosis
Onychomycosis
Device: Nail Genesis DLSO Product
Device: Nail Genesis DLSO Product (vehicle only)

The study will determine the optimal dosing regimen of LNA043 in patients with knee osteoarthritis (OA).

Active, not recruiting
Osteoarthritis
Drug: LNA043 Dosing Regimen A
Drug: Placebo

Endometriosis is a painful disorder of the uterus affecting 6-10% of women of childbearing age. Endometriosis affects daily activities, social relati...

Enrolling
Endometriosis
Drug: Elagolix
Drug: Placebo

Study of the contraceptive efficacy, cycle control, safety, and tolerability of MR-100A-01 in approxmiately 1200 women for up to 13 cycles

Active, not recruiting
Contraception
Drug: MR-100A-01

Trial sponsors

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