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Ianalumab
TAK-279
DDY391
Anifrolumab
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Obefazimod
Belimumab
Cenerimod
Obinutuzumab
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Active trials

17 of 21 total trials

A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis

The purpose of this study is to evaluate efficacy, safety and tolerability of s.c. ianalumab administered in participants with diffuse cutaneous syst...

Enrolling
Diffuse Cutaneous Systemic Sclerosis
Drug: Ianalumab
Drug: Placebo
Status recently updated

To evaluate efficacy, safety, and tolerability of DDY391 up to 52 weeks in participants with Sjögren's disease (SjD) and to determine the dose respon...

Not yet enrolling
Enrolling
Sjögren's Disease
Drug: Placebo
Drug: DDY391
Locations recently updated

CKJX839D12302 is a pivotal Phase III study designed to test the hypothesis that treatment with inclisiran sodium 300 milligram (mg) subcutaneous (s.c...

Active, not recruiting
Primary Prevention of Atherosclerotic Cardiovascular Disease
Drug: Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL
Drug: Placebo in 1.5ml

The main purpose of the proposed study is to evaluate the efficacy of efgartigimod PH20 SC in patients with moderate-to-severe Primary Sjögren's Dise...

Active, not recruiting
Primary Sjogrens Disease
Biological: Efgartigimod PH20 SC
Other: Placebo PH20 SC

Crohn's disease (CD) is a long-lasting condition causing inflammation that can affect any part of the gut. The purpose of this study is to evaluate t...

Enrolling
Crohn's Disease
Drug: Placebo
Drug: TAK-279

The main aim of this study is to learn if TAK-279 reduces bowel inflammation and symptoms compared to placebo. Another aim is to compare any medical...

Active, not recruiting
Ulcerative Colitis
Drug: TAK-279
Drug: Placebo

Psoriatic arthritis (PsA) is a long-term inflammatory disease that affects the joints and skin.The purpose of this study is to check how safe zasocit...

Enrolling
Psoriatic Arthritis
Drug: Zasocitinib

This study has 3 treatment phases, a 12-Week Induction Phase, a 40-Week Maintenance Phase, and a 48-Week Extension Phase.The objective is to evaluate...

Enrolling
Moderately to Severely Active Crohn Disease
Drug: Obefazimod
Other: Placebo

The goal of this clinical study is to learn about the long-term safety and tolerability of cenerimod in adult patients with moderate to severe sympto...

Invitation-only
Lupus Erythematosus, Systemic
Drug: Cenerimod

The goal of this clinical trial is to learn if drug Nu-3 works to treat mildly infected diabetic foot ulcers in adults with Type 1 or Type 2 diabetes...

Enrolling
Diabetic Foot Ulcers (DFUs)
Drug: Antimicrobial agent

The purpose of this study is to evaluate long-term safety and tolerability of ianalumab in participants with systemic lupus erythematosus who have pr...

Enrolling
Systemic Lupus Erythematosus
Drug: Placebo
Drug: Ianalumab

Phase 3 Study of Telitacicept in Active Primary Sjögren's Disease (UPSTREAM SjD)

Enrolling
Primary Sjogren's Disease
Biological: Telitacicept
Drug: Placebo

The trial will evaluate efficacy, safety and tolerability of ianalumab compared to placebo, given as monthly subcutaneous (s.c.) injection on top of...

Active, not recruiting
Systemic Lupus Erythematosus
Drug: placebo
Drug: ianalumab

The trial will evaluate efficacy, safety and tolerability of two regimens of ianalumab compared to placebo, given as monthly or quarterly subcutaneou...

Active, not recruiting
Systemic Lupus Erythematosus
Drug: Placebo
Drug: Ianalumab

The goal of this clinical study is to assess the efficacy and safety of LUPKYNIS® in combination with belimumab, obinutuzumab or anifrolumab at induc...

Enrolling
Lupus Nephritis
Drug: mycophenolic acid analog (MPAA)
Drug: LUPKYNIS

The purpose of this study is to demonstrate the efficacy and safety of ianalumab (VAY736) 300 mg administered subcutaneously (s.c.) monthly for 52 we...

Enrolling
Sjögren´s Disease
Drug: Placebo
Drug: VAY736

The purpose of this study is to demonstrate the comparability of ianalumab exposure following the sub-cutaneous (s.c.) administration of one injectio...

Active, not recruiting
Sjögrens Disease
Systemic Lupus Erythematosus
Biological: VAY736 2ml AI
Biological: VAY736 1ml PFS

Trial sponsors

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