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Nucleus Network | Nucleus Network - Melbourne, Australia

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Active trials

12 of 103 total trials

A Clinical Trial to Access Pharmacokinetic Profiles and Safety of IVL3003.

A Clinical Trial to Assess Pharmacokinetic Profiles and Safety of IVL3003

Active, not recruiting
Alzheimer Disease
Drug: Aricept Tablet
Drug: IVL3003

The purpose of this study is to evaluate the safety and tolerability, and pharmacokinetics of DT-216P2 administered multiple ascending doses in patie...

Enrolling
Friedreich Ataxia
Drug: DT-216P2

The purpose of this study is to assess the safety, tolerability and pharmacokinetics of single and multiple intravenous doses of BWC0977 when adminis...

Begins enrollment in 1 month
Antimicrobial Drug Resistance
Infectious Diseases
Drug: Placebo
Drug: BWC0977

The purpose of this study is to evaluate the relative bioavailability of capsule and tablet formulations of TYRA-300-B01, and to evaluate the safety,...

Active, not recruiting
Healthy
Drug: TYRA-300-B01

A Phase 1 study will assess the safety, tolerability, and pharmacokinetics of Atorvo+™ in healthy adult participants..

Enrolling
Coronary Heart Disease
Dyslipidemias
Drug: Atorvo+™ +CBD (Arm 3)
Drug: Atorvo+™ +CBD (Arm 2)

This is an open-label, two-part study to evaluate the safety, tolerability, pharmacokinetics and immunogenicity of SHR-A1811 and preliminary anti-tum...

Active, not recruiting
Advanced Solid Tumors
Drug: SHR-A1811

This is a phase 1, randomized, First in Human (FIH), double-blinded, placebo-controlled study to assess the safety, tolerability, and PK of RSN0402 i...

Enrolling
Idiopathic Pulmonary Fibrosis
Lung; Disease, Interstitial, With Fibrosis
Drug: Placebo
Drug: RSN0402 Part 2

The purpose of this study is to test the safety of mRNA-0184 in healthy participants.

Enrolling
Healthy Participants
Drug: mRNA-0184
Status recently updated

First-in-Human Phase 1, Single-Center, Randomized, Blinded, Placebo-Controlled Trial in Healthy Adults to Evaluate the Safety, Tolerability, and Phar...

Begins enrollment this month
Enrolling
Healthy Volunteers
Drug: AN2-502998
Drug: Placebo

The purpose of this study is to assess the pharmacokinetics, safety, tolerability and food effect of investigational drug MRX1 in healthy adults.

Not yet enrolling
Pharmacokinetics
Drug: Cannabidiol

The purpose of Parts D and E of this Phase 1 study are to evaluate the safety, tolerability, and pharmacokinetics of multiple dose combinations of SI...

Not yet enrolling
Cystic Fibrosis (CF)
Drug: Placebo SION-109
Drug: SION-109

The purpose of this study is to evaluate the safety and tolerability of intravenously (IV) administered mRNA-0184 under different infusion conditions.

Enrolling
Healthy Participants
Drug: mRNA-0184

Trial sponsors

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