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NYU Langone Hospital - Long Island | Dialysis and Nephrology

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Active trials

14 of 130 total trials

A Study Evaluating the Safety, Activity, and Pharmacokinetics of Divarasib in Combination With Other Anti-Cancer Therapies in Participants With Previously Untreated Advanced or Metastatic Non-Small Cell Lung Cancer With a KRAS G12C Mutation (Krascendo 170)

The purpose of this study is to evaluate the safety, pharmacokinetics (PK), and activity of divarasib combined with other anti-cancer therapies in pa...

Enrolling
Non-Small Cell Lung Cancer
Drug: Pembrolizumab
Drug: Carboplatin

This clinical trial is studying advanced or metastatic solid tumors. Once a solid tumor has grown very large in one spot or has spread to other place...

Active, not recruiting
Ovarian Neoplasms
Carcinoma, Non-Small-Cell Lung
Drug: disitamab vedotin

This study is designed to evaluate the safety and efficacy of ifinatamab deruxtecan (I-DXd) in combination with immune checkpoint inhibitor (ICI) ate...

Enrolling
Extensive Stage-small Cell Lung Cancer
Drug: Carboplatin
Drug: Ifinatamab deruxtecan

The purpose of this study is to evaluate the efficacy of olezarsen as compared to placebo on the percent change in fasting triglycerides (TG) from ba...

Active, not recruiting
Severe Hypertriglyceridemia
Drug: Placebo
Drug: Olezarsen

The main purpose of this study is to investigate the effect of retatrutide on renal function in participants with overweight or obesity and chronic k...

Active, not recruiting
Overweight or Obesity
CKD
Drug: Placebo
Drug: Retatrutide

The purpose of this study is to assess the safety and efficacy of two doses of Deucravacitinib in adult participants with Active Sjögren's Syndrome.

Enrolling
Sjögren's Syndrome
Other: Placebo
Drug: Deucravacitinib

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor D...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

To establish the safety and effectiveness of the Edwards PASCAL Transcatheter Valve Repair System in patients with degenerative mitral regurgitation...

Enrolling
Degenerative Mitral Valve Disease
Functional Mitral Regurgitation
Device: Edwards PASCAL System
Device: Abbott Mitraclip System

To assess the safety and tolerability of increasing doses of PF-07104091 and to estimate the Maximum Tolerated Dose (MTD) and/or select the Recommend...

Active, not recruiting
Breast Cancer
Small Cell Lung Cancer
Drug: PF-07104091 monotherapy dose expansion (ovarian)
Drug: PF-07104091 + palbociclib + fulvestrant

This study objective is to establish the safety and effectiveness of the Edwards SAPIEN 3 / SAPIEN 3 Ultra / SAPIEN 3 Ultra RESILIA Transcatheter Hea...

Enrolling
Aortic Valve Stenosis
Aortic Stenosis, Calcific
Device: SAPIEN 3 / SAPIEN 3 Ultra / SAPIEN 3 Ultra RESILIA

RADIANCE CAP is a non-randomized study designed to allow for continued access to ultrasound renal denervation therapy via the Paradise System, and to...

Active, not recruiting
Hypertension
Hypertension, Resistant to Conventional Therapy
Device: Renal Denervation

This study is to understand if the study vaccine (called VLA15) is safe in healthy children.We are looking for children who:* are healthy* are age 5...

Active, not recruiting
Lyme Disease
Other: Normal Saline
Biological: VLA15

This phase III trial studies how well trastuzumab emtansine (T-DM1) and tucatinib work in preventing breast cancer from coming back (relapsing) in pa...

Enrolling
Anatomic Stage III Breast Cancer AJCC V8
Anatomic Stage IIIA Breast Cancer AJCC V8
Biological: Trastuzumab Emtansine
Other: Quality-of-Life Assessment

Multi-center, global, prospective, non-randomized, interventional, pre-market trial. All subjects enrolled with receive the study device.

Enrolling
Mitral Valve Regurgitation
Device: Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR)

Trial sponsors

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NRG Oncology logo
Pfizer logo
Alliance for Clinical Trials in Oncology logo
NYU Langone Health logo
ECOG-ACRIN Cancer Research Group logo
Edwards Lifesciences logo
Lilly logo
Regeneron Pharmaceuticals logo

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