Oklahoma Medical Research Foundation | Oklahoma City, OK

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825 N.E. 13th Street, Oklahoma City, Oklahoma, United States of America
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9 of 115
Status: Active
Trial type: Interventional
Funder type: Industry

A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Ocrelizumab In Patients With Multiple Sclerosis (OLERO)

This is a Phase IIIb, single-arm, multicenter, OLE study. Participants receiving ocrelizumab as an investigational medicinal product (IMP) in a Roche...

Active, not recruiting
Multiple Sclerosis
Drug: Ocrelizumab

The purpose of this study is to evaluate the effectiveness, safety and tolerability of Afimetoran in participants with active Systemic Lupus Erythema...

Systemic Lupus Erythematosus
Drug: Afimetoran
Other: Placebo

This post-marketing study is designed to compare the safety of baricitinib versus tumor necrosis factor (TNF) inhibitors with respect to venous throm...

Active, not recruiting
Rheumatoid Arthritis
Drug: Baricitinib
Drug: TNF Inhibitor

The purpose of this study is to assess the efficacy and safety of zetomipzomib (30 mg or 60 mg) compared with placebo in achieving renal response aft...

Lupus Nephritis
Drug: placebo
Drug: zetomipzomib

The purpose of this study is to evaluate the effectiveness and safety of deucravacitinib compared with placebo in an active moderate to severe System...

Systemic Lupus Erythematosus
Other: Placebo
Drug: Deucravacitinib

This study will evaluate the efficacy, safety, and pharmacokinetics of obinutuzumab compared with placebo in patients with International Society of N...

Active, not recruiting
Lupus Nephritis
Drug: Obinutuzumab
Drug: MMF

The purpose of this study is to better understand the mechanism of action (MoA) of cladribine tablets by exploring the effect on central nervous syst...

Active, not recruiting
Multiple Sclerosis
Multiple Sclerosis, Relapsing-Remitting
Drug: Cladribine

This study to examines the impact of anifrolumab on disease activity, immune phenotypes, and development of neutralizing antibodies to quadrivalent i...

Systemic Lupus Erythematosus (SLE)
Drug: Standard of Care
Drug: Anifrolumab

This study is a prospective, multi-center, randomized, double blinded, placebo-controlled study of OCR treatment-discontinuation in patients with ear...

Multiple Sclerosis
Drug: Ocrelizumab
Drug: Placebo for Ocrelizumab

Trial conditions

Systemic Lupus Erythemat... (39 trials)
Arthritis (12 trials)
Lung Cancer (11 trials)
Multiple Sclerosis (11 trials)
Rheumatoid Arthritis (11 trials)
Sclerosis (10 trials)
Melanoma (5 trials)
Non-Small-Cell Lung Carc... (5 trials)
Breast Cancer (4 trials)
Leukemia (4 trials)

And 61 more

Clinical trials

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