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Daclatasvir
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Active trials

13 of 216 total trials

A Phase 1 Study to Evaluate the Pharmacokinetics of JDQ443 in Participants With Hepatic Impairment Compared to Matched Healthy Control Participants.

The purpose of this study is to evaluate the effect of hepatic impairment on the systemic pharmacokinetics (PK), safety, and tolerability of JDQ443 i...

Enrolling
Small Cell Lung Carcinoma
Drug: JDQ443

The study investigates an investigational drug called etavopivat in participants with hepatic impairments and participants with normal hepatic functi...

Enrolling
Liver Diseases
Drug: Etavopivat

The purpose of this study is to characterize the single-dose pharmacokinetic (PK) of apalutamide in participants with severe hepatic impairment relat...

Enrolling
Hepatic Impairment
Drug: Apalutamide
Status recently updated

The primary objective of the study is to evaluate the pharmacokinetics (PK) of avacopan and metabolite (M1) after a single dose of avacopan in partic...

Not yet enrolling
Enrolling
End-Stage Renal Disease (ESRD)
Drug: Avacopan

The main purpose of this study is to assess the amount of study drug (LY3473329) that reaches the bloodstream and the time it takes for the body to g...

Enrolling
Renal Insufficiency
Drug: LY3473329

The main purpose of this study is to measure how much of LY3502970 gets into the bloodstream and how long it takes the body to eliminate it in partic...

Enrolling
Healthy
Hepatic Insufficiency
Drug: LY3502970

The main aim of this study is to find out how the body processes 1 dose of TAK-279 (pharmacokinetics) in participants with liver problems compared to...

Enrolling
Hepatic Impairment
Healthy Volunteers
Drug: TAK-279

The purpose of this study is to assess the drug levels of a single oral dose of repotrectinib in participants with moderate and severe HI, and in hea...

Enrolling
Hepatic Impairment
Healthy Volunteers
Drug: Repotrectinib

The rationale of this study is to evaluate the impact of renal function on the PK, safety, and tolerability of VIR-2218 in participants with normal r...

Enrolling
Renal Impairment
Drug: VIR-2218

Researchers are looking for a better way to treat people who have chronic kidney disease (CKD).CKD is a condition in which the kidneys' ability to wo...

Enrolling
Hepatic Impairment
Chronic Kidney Disease
Drug: BAY3283142

This study is open to people with and without severe liver problems. People can join the study if they are 18 to 80 years of age and have a body mass...

Enrolling
Healthy
Liver Diseases
Drug: Avenciguat (BI 685509)

This study will investigate the pharmacokinetics, safety, and tolerability of DZD9008 in subjects with hepatic impairment compared to subjects with n...

Enrolling
Hepatic Impairment
Drug: DZD9008

The goals of this study are to measure the amount of bulevirtide (BLV) that gets into the blood stream and how long it takes to get rid of it, measur...

Enrolling
Chronic Hepatitis D Infection
Drug: Bulevirtide

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