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Orlando Immunology Center | Orlando, FL

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Top treatments

Emtricitabine
Islatravir
Sofosbuvir
Ribavirin
Tenofovir Alafenamide
Doravirine
Lenacapavir
TAF
Bictegravir
Interferon

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Active trials

22 of 148 total trials

A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)

Researchers are looking for new ways to treat HIV-1 (Human Immunodeficiency Virus Type 1). The usual (standard) treatment for HIV-1 is antiretroviral...

Enrolling
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Drug: ISL/ULO
Drug: ULO

Researchers are looking for new medicines to prevent HIV-1 (Human Immunodeficiency Virus Type 1) infection.The goals of this study are to learn:* If...

Enrolling
HIV Pre-Exposure Prophylaxis
Human Immunodeficiency Virus (HIV)
Drug: Placebo to MK-8527
Drug: MK-8527

The purpose of this study is to evaluate the antiviral effect, safety, tolerability, and pharmacokinetics of STP0404 in adult participants living wit...

Enrolling
HIV-1-infection
Drug: High-dose STP0404 (Pirmitegravir)
Drug: Low-dose STP0404 (Pirmitegravir)

The purpose of this study is to evaluate the safety and tolerability of DOR/ISL in adult participants with HIV-1 who had been previously treated with...

Active, not recruiting
HIV Infection
Drug: DOR/ISL

Investigators are trying to find better treatments for people with HIV-1. In this clinical study, investigators want to see how well a new treatment...

Active, not recruiting
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Drug: BIC/FTC/TAF
Drug: ULO

The goal of this study is to test the effectiveness, safety, and tolerability of the combination of broadly neutralizing antibodies (bNAbs) (teropavi...

Active, not recruiting
HIV Infection
Drug: Lenacapavir Injection
Drug: Lenacapavir Tablet

The primary objectives of this study are to evaluate the safety and tolerability of a switch to Doravirine/Islatravir (DOR/ISL) compared with continu...

Active, not recruiting
HIV-1 Infection
Drug: DOR/ISL
Drug: ART

The primary objectives of this study are to evaluate the antiretroviral activity of a switch to Doravirine/Islatravir (DOR/ISL) compared with continu...

Active, not recruiting
HIV-1 Infection
Drug: BIC/FTC/TAF
Drug: DOR/ISL

The RECOVER study is a self-controlled case series to evaluate whether the addition of Fostemsavir (Rukobia) to a stable HIV regimen in virologically...

Active, not recruiting
HIV-1-infection
Drug: Fostemsavir 600 MG [Rukobia]

This is a randomized, active-controlled, double-blind clinical study designed to evaluate the antiretroviral activity, safety, and tolerability of do...

Active, not recruiting
HIV-1 Infection
Drug: BIC/FTC/TAF
Drug: Placebo to DOR/ISL

TMB-365 is a monoclonal antibody that binds to the CD4 receptor. TMB-380, aka VRC07-523LS is a monoclonal antibody that binds to HIV. Both interfere...

Enrolling
HIV -1 Infection
Drug: TMB-380
Drug: Baseline ART

The safety and tolerability of MK-8591A, a 2-drug fixed dose combination (FDC) of doravirine (100mg) and islatravir (0.75mg) \[DOR/ISL 100 mg/0.75 mg...

Active, not recruiting
HIV-1 Infection
Drug: MK-8591A

A multicenter, randomized, parallel-group, placebo-controlled, double-blind, Phase 1/2a clinical study to investigate the safety, tolerability, immun...

Active, not recruiting
Retroviridae Infections
Immunologic Deficiency Syndrome, Acquired
Biological: Ad26.Mos4.HIV
Biological: PGT121

The primary objective of this study is to evaluate the efficacy of oral weekly islatravir (ISL) in combination with lenacapavir (LEN) in virologicall...

Active, not recruiting
HIV-1 Infection
Drug: ISL/LEN FDC
Drug: B/F/TAF

The goal of this study is to evaluate the efficacy of the study drugs, lenacapavir (LEN) in preventing HIV infection, in participants ≥ 16 years of a...

Active, not recruiting
Pre-Exposure Prophylaxis of HIV Infection
Drug: Sub-cutaneous (SC) Lenacapavir (LEN)
Drug: PTM Oral LEN

The goal of this clinical study is to learn more about the experimental drugs GS-1720 (an oral, long-acting integrase strand transfer inhibitor (INST...

Active, not recruiting
HIV-1-infection
Drug: GS-4182
Drug: Bictegravir/emtricitabine/tenofovir alafenamide

The goal of this clinical study is to learn more about the experimental drugs GS-1720 and GS-4182; to compare the combination of GS-1720 and GS-4182...

Active, not recruiting
HIV-1-Infection
Drug: Placebo to Match BVY
Drug: Placebo to Match GS1720/GS-4182 FDC

The goal of this clinical study is to learn about the safety and efficacy of switching to once weekly tablet of islatravir/lenacapavir (ISL/LEN) regi...

Active, not recruiting
HIV-1-infection
Drug: B/F/TAF
Drug: PTM ISL/LEN

The goal of this clinical study is to learn more about the safety and efficacy of switching to a once weekly tablet of islatravir/lenacapavir (ISL/LE...

Active, not recruiting
HIV-1-Infection
Drug: Antiretroviral Combinations
Drug: ISL/LEN

The goal of this clinical study is to learn more about the effects of switching to the study drugs, bictegravir (BIC) plus lenacapavir (LEN), versus...

Active, not recruiting
HIV-1-infection
Drug: Stable Baseline Regimen
Drug: Bictegravir

Trial sponsors

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