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ASST Papa Giovanni XXIII | Ospedale di Bergamo - SC Malattie Endocrine-Diabetologia

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Top conditions

Top treatments

Nivolumab
Odevixibat
Finerenone
Vericiguat
Axicabtagene
Ziltivekimab
Ezetimibe
Sacituzumab
Enzalutamide
MK-3475-975

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This site is a part of ASST Papa Giovanni XXIII

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Active trials

19 of 27 total trials

A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Heart Failure and Inflammation (HERMES)

This study will be done to see if ziltivekimab can be used to treat people living with heart failure and inflammation. Participants will either get z...

Enrolling
Heart Failure
Drug: Placebo
Drug: Ziltivekimab

This is a Phase 2, double-blind, randomized, placebo-controlled study to evaluate the efficacy and safety of sotatercept versus placebo in adults wit...

Enrolling
Hypertension, Pulmonary
Drug: Placebo
Drug: Sotatercept 0.3 mg/kg escalating to 0.7 mg/kg

Researchers are looking for a better way to treat men at high-risk of biochemical recurrence (BCR) of prostate cancer.BCR means that in men who had p...

Enrolling
Biochemically Recurrent Prostate Cancer
Other: Placebo matching darolutamide
Drug: Darolutamide (BAY1841788, Nubeqa)

The purpose of this study is to assess the efficacy, safety, and immunogenicity of ABP 206 compared with Nivolumab in Subjects with Treatment-Naïve U...

Enrolling
Melanoma
Drug: ABP 206
Drug: Nivolumab

The purpose of this study is to investigate the pharmacokinetic (PK) similarity and efficacy, safety, and immunogenicity of ABP 206 compared with OPD...

Enrolling
Melanoma
Drug: EU-authorized Nivolumab
Drug: ABP 206

The purpose of this study is to assess the patient's preference for nivolumab subcutaneous (SC) or nivolumab + relatlimab fixed-dose combination (FDC...

Enrolling
Melanoma
Drug: nivolumab+rHuPH20
Drug: relatlimab+nivolumab+rHuPH20

Researchers are looking for a better way to treat people who have chronic heart failure with reduced ejection fraction. Chronic heart failure with re...

Active, not recruiting
Chronic Heart Failure With Reduced Ejection Fraction
Drug: Vericiguat (BAY1021189) 5 mg

Finerenone works by blocking a group of proteins, called mineralocorticoid receptor. An increased stimulation of mineralocorticoid receptor is known...

Enrolling
Chronic Kidney Disease
Type 2 Diabetes Mellitus
Drug: Finerenone (BAY94-8862 ) 20 mg
Drug: Finerenone Placebo

Researchers are looking for a better way to prevent an ischemic stroke which occurs when a blood clot travelled to the brain in people who within the...

Enrolling
High-risk Transient Ischemic Attack
Acute Non-cardioembolic Ischemic Stroke
Drug: Asundexian (BAY2433334)
Drug: Placebo

An Open-label Extension Study to Evaluate Long-term Efficacy and Safety of Odevixibat (A4250) in Children with Biliary Atresia

Invitation-only
Biliary Atresia
Drug: Odevixibat

Double-blind, randomized, placebo-controlled, Phase 3 study to investigate the efficacy and safety of odevixibat compared to placebo in children with...

Active, not recruiting
Biliary Atresia
Drug: Odevixibat
Drug: Placebo

The goal of the study is to investigate the efficacy and safety of Lenodiar Pediatric (product under investigation) for the treatment of Chronic Diar...

Enrolling
Chronic Diarrhoea of Infants and/or Young Children
Device: Lenodiar Pediatric
Other: Placebo

This is a Phase 3, multicenter, randomized, controlled, parallel-group, open-label study to evaluate the effects of plasma exchange using human serum...

Enrolling
Acute-On-Chronic Liver Failure
Other: Standard Medical Treatment
Biological: SMT + PE-A 5%

The primary objective of the study is to compare disease-free survival (DFS) of patients with high-risk cutaneous squamous cell carcinoma (CSCC) trea...

Enrolling
Cutaneous Squamous Cell Carcinoma
Drug: Placebo
Drug: Cemiplimab

The goal of this clinical study is test how well the study drug, axicabtagene ciloleucel, works in participants with relapsed/refractory follicular l...

Enrolling
Relapsed/Refractory Follicular Lymphoma
Drug: Cyclophosphamide
Drug: Vincristine

The purpose of this study is to assess the efficacy and safety of treatment with definitive chemoradiotherapy (dCRT) + pembrolizumab (MK-3475) compar...

Active, not recruiting
Gastroesophageal Junction Carcinoma (GEJC)
Esophageal Squamous Cell Carcinoma (ESCC)
Drug: levoleucovorin
Biological: pembrolizumab
Locations recently updated

The goal of this clinical study is to see if sacituzumab govitecan-hziy (SG) can improve life spans of people with HR+/HER2- metastatic breast cancer...

Enrolling
Locally Advanced or Unresectable Metastatic Breast Cancer
Stage IV Breast Cancer
Drug: Paclitaxel
Drug: Capecitabine
Locations recently updated

The purpose of the study is to evaluate the safety and efficacy of talazoparib in combination with enzalutamide compared with placebo in combination...

Active, not recruiting
Prostate Cancer
Drug: Placebo plus enzalutamide
Drug: talazoparib plus enzalutamide

This study is conducted to see if ziltivekimab reduces the risk of having cardiovascular events (for example heart attack and stroke) in people with...

Enrolling
Chronic Kidney Disease
Inflammation
Drug: Placebo (Ziltivekimab B)
Drug: Placebo (Ziltivekimab C)

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