Parkinson's Disease and Movement Disorders Center of Boca Raton | Boca Raton, FL

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951 NW 13th Street, Bldg. 5E, Boca Raton, Florida, United States of America

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Active trials

16 of 66 total trials

A Phase 2a Study of TPN-101 in Patients With Progressive Supranuclear Palsy (PSP)

This is a Phase 2a study to assess the safety and tolerability of TPN-101 patients with PSP.

Active, not recruiting
Progressive Supranuclear Palsy
Drug: Placebo
Drug: TPN-101, 100 mg/day

In this study, researchers will learn more about a study drug called BIIB122 in participants with early-stage Parkinson's disease (PD). In this study...

Parkinson Disease
Drug: BIIB122
Drug: BIIB122-Matching Placebo

This is a multicenter, randomized, double-blind, placebo-controlled study that will evaluate the efficacy and safety of intravenous (IV) prasinezumab...

Active, not recruiting
Parkinsons Disease
Drug: Prasinezumab
Drug: Placebo

This multicenter, randomized, double-blind, placebo-controlled, Phase 2 study will evaluate the efficacy of intravenous prasinezumab (RO7046015/PRX00...

Active, not recruiting
Parkinson's Disease
Drug: RO7046015
Drug: Placebo

ORION Trial is a trial to evaluate the efficacy and safety of AMX0035 in participants with Progressive Supranuclear Palsy (PSP), consisting of a rand...

Neurodegenerative Diseases
Other: Placebo
Drug: AMX0035

The goal of this clinical study is to compare Felix NeuroAI Wristband and sham device in patients with essential tremor. The main question it aims to...

Essential Tremor
Device: Felix NeuroAI Wristband
Device: Sham Device

This study is designed to evaluate the safety and efficacy of dipraglurant in PD patients with dyskinesia (randomized 1:1 to receive active or placeb...

Parkinson Disease
Dyskinesia, Drug-Induced
Drug: Dipraglurant
Drug: Placebo

This is a multicenter, 12-week, placebo-controlled clinical trial of CVN424 150 milligrams (mg) tablets in early, untreated Parkinson's Disease (PD)....

Parkinson's Disease
Drug: Placebo
Drug: CVN424 150 mg

The purpose of this randomized, double-blind, placebo-controlled study is to assess the efficacy of BIA 28-6156 over placebo in delaying clinical mea...

Parkinson's Disease
Drug: Placebo
Drug: BIA 28-6156 60 mg

Parkinson's disease (PD) is a neurological condition, which affects the brain. PD gets worse over time, but how quickly it progresses varies a lot fr...

Active, not recruiting
Parkinson's Disease (PD)
Drug: ABBV-951

The objective of this randomized, double-blinded, placebo-controlled Phase 1 investigation is to evaluate the safety and potential clinical effect of...

Multiple System Atrophy
Procedure: Sham (Placebo) Surgery
Biological: AAV2-GDNF gene therapy
Locations recently updated

This is a Phase 3, multi-center, randomized withdrawal study to evaluate the efficacy and durability of ampreloxetine in participants with MSA and sy...

MSA - Multiple System Atrophy
Symptomatic Neurogenic Orthostatic Hypotension
Drug: Ampreloxetine
Drug: Placebo

A 76-week safety and efficacy study of simufilam (PTI-125) given twice daily to participants with mild-to-moderate Alzheimer's disease (AD) for 76 we...

Active, not recruiting
Alzheimer Disease
Drug: Placebo
Drug: Simufilam

This is a double-blinded, controlled, randomized clinical trial (RCT) to establish the safety and efficacy of a non-invasive neuromodulation device f...

Parkinson Disease
Parkinson's Disease and Parkinsonism
Device: Non-invasive brainstem stimulation

Upper limb essential tremor (UL ET) is a movement disorder characterized by postural and/or kinetic tremor. It can cause difficulty with everyday tas...

Active, not recruiting
Upper Limb Essential Tremor (UL ET)
Drug: Placebo for BOTOX
Biological: BOTOX

Multi-center, randomized, double-blind, placebo-controlled, 6- month study in subjects with mild to moderate Dementia with Lewy Bodies.

Active, not recruiting
Dementia With Lewy Bodies
Drug: CT1812

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