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Parkinson's Disease and Movement Disorders Center of Boca Raton | Boca Raton, FL

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Levodopa
PF-06649751
ABBV-951
CVN424
IPX203
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ENT-01
APL-130277
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Active trials

18 of 74 total trials

A Phase 2 Study of ONO-2808 in Patients With Multiple System Atrophy

This is a Phase 2, double-blind, parallel-group, placebo-controlled study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and...

Enrolling
Multiple System Atrophy (MSA)
Drug: ONO-2808
Drug: Placebo

This is a Phase 2a study to assess the safety and tolerability of TPN-101 patients with PSP.

Active, not recruiting
Progressive Supranuclear Palsy
Drug: Placebo
Drug: TPN-101, 400 mg/day

The objective of this randomized, surgically controlled, double-blinded, Phase 2 study is to evaluate the safety and efficacy of AAV2-GDNF delivered...

Enrolling
Parkinson Disease
Procedure: Control Surgery
Drug: AAV2-GDNF Gene therapy

In this study, researchers will learn more about a study drug called BIIB122 in participants with early-stage Parkinson's disease (PD). In this study...

Enrolling
Parkinson Disease
Drug: BIIB122-Matching Placebo
Drug: BIIB122

This is a multicenter, randomized, double-blind, placebo-controlled study that will evaluate the efficacy and safety of intravenous (IV) prasinezumab...

Active, not recruiting
Parkinsons Disease
Drug: Placebo
Drug: Prasinezumab

This multicenter, randomized, double-blind, placebo-controlled, Phase 2 study will evaluate the efficacy of intravenous prasinezumab (RO7046015/PRX00...

Active, not recruiting
Parkinson's Disease
Drug: RO7046015
Drug: Placebo
Status recently updated

A35-009 (ORION) is a Phase 2b/3 trial to evaluate the efficacy and safety of AMX0035 in participants with Progressive Supranuclear Palsy (PSP), consi...

Enrolling
Active, not recruiting
PSP
Neurodegenerative Diseases
Other: Placebo
Drug: AMX0035

The goal of this clinical study is to compare Felix NeuroAI Wristband and sham device in patients with essential tremor. The main question it aims to...

Active, not recruiting
Essential Tremor
Device: Felix NeuroAI Wristband
Device: Sham Device

This is a multicenter, 12-week, placebo-controlled clinical trial of CVN424 150 milligrams (mg) tablets in early, untreated Parkinson's Disease (PD)....

Active, not recruiting
Parkinson's Disease
Drug: Placebo
Drug: CVN424 150 mg

The purpose of this randomized, double-blind, placebo-controlled study is to assess the efficacy of BIA 28-6156 over placebo in delaying clinical mea...

Active, not recruiting
Parkinson's Disease
Drug: Placebo
Drug: BIA 28-6156 60 mg

Parkinson's disease (PD) is a neurological condition, which affects the brain. PD gets worse over time, but how quickly it progresses varies a lot fr...

Active, not recruiting
Parkinson's Disease (PD)
Drug: ABBV-951

The objective of this randomized, double-blinded, placebo-controlled Phase 1 investigation is to evaluate the safety and potential clinical effect of...

Enrolling
Multiple System Atrophy
Procedure: Sham (Placebo) Surgery
Biological: AAV2-GDNF gene therapy
Locations recently updated

This is a Phase 3, multi-center, randomized withdrawal study to evaluate the efficacy and durability of ampreloxetine in participants with MSA and sy...

Enrolling
MSA - Multiple System Atrophy
Symptomatic Neurogenic Orthostatic Hypotension
Drug: Ampreloxetine
Drug: Placebo

A 76-week safety and efficacy study of simufilam (PTI-125) given twice daily to participants with mild-to-moderate Alzheimer's disease (AD) for 76 we...

Active, not recruiting
Alzheimer Disease
Drug: Placebo
Drug: Simufilam

This is a double-blinded, controlled, randomized clinical trial (RCT) to establish the safety and efficacy of a non-invasive neuromodulation device f...

Active, not recruiting
Parkinson Disease
Parkinson's Disease and Parkinsonism
Device: Non-invasive brainstem stimulation

Upper limb essential tremor (UL ET) is a movement disorder characterized by postural and/or kinetic tremor. It can cause difficulty with everyday tas...

Active, not recruiting
Upper Limb Essential Tremor (UL ET)
Drug: Placebo for BOTOX
Biological: BOTOX

Multi-center, randomized, double-blind, placebo-controlled, 6- month study in subjects with mild to moderate Dementia with Lewy Bodies.

Active, not recruiting
Dementia With Lewy Bodies
Drug: CT1812
Locations recently updated

This is a randomized, double-blind, placebo-controlled, multicenter study in participants with Parkinson's disease (PD) with motor fluctuations. Part...

Enrolling
Parkinson Disease
Drug: Placebo
Drug: CVN424 75 mg

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