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Active trials

12 of 66 total trials

A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE

The purpose of this study is to evaluate whether milvexian compared to placebo reduce the risk of recurrent ischemic stroke.

Enrolling
Ischemic Stroke; Ischemic Attack, Transient
Drug: Placebo
Drug: Milvexian

The purpose of this study is to evaluate the efficacy and safety of pemigatinib versus gemcitabine plus cisplatin chemotherapy in first-line treatmen...

Active, not recruiting
Metastatic Cholangiocarcinoma
Unresectable Cholangiocarcinoma
Drug: Gemcitabine
Drug: Cisplatin

The ALLEVIATE-HF study is a prospective, randomized, controlled, blinded, multi-site, interventional, investigational device exemption (IDE) pivotal...

Active, not recruiting
Heart Failure NYHA Class II
Heart Failure NYHA Class III
Device: Reveal LINQ™ Insertable Cardiac Monitor with investigational ALLEVIATE-HF RAMware download
Other: Medication intervention

This is a multicenter, randomized, open-label study of Tumor Treating Fields (TTFields) at 150 kHz to the thorax using the NovoTTF-200T System with I...

Enrolling
Non-small Cell Lung Cancer
Drug: Pembrolizumab (MK-3475) 200 mg
Device: NovoTTF-200T

This is a prospective, multicenter, double-blind, placebo-controlled, randomized Phase 3 study. The purpose of the study is to obtain evidence of eff...

Active, not recruiting
Endometrial Cancer
Drug: Matching placebo for selinexor
Drug: Selinexor

Study to compare the safety and efficacy of oregovomab versus placebo, administered in combination with specific cycles of a standard six-cycle chemo...

Active, not recruiting
Ovarian Neoplasms
Fallopian Tube Adenocarcinoma
Drug: Paclitaxel
Biological: Placebo

RADIANCE CAP is a non-randomized study designed to allow for continued access to ultrasound renal denervation therapy via the Paradise System, and to...

Active, not recruiting
Hypertension
Hypertension, Resistant to Conventional Therapy
Device: Renal Denervation

This is an open label, multicenter, single arm phase II study to evaluate the efficacy and safety of ribociclib and ET in patients with locoregional...

Active, not recruiting
Hormone Receptor-positive Breast Cancer
Locoregional Recurrence
Drug: Fulvestrant
Drug: Ribociclib

This study evaluates navtemadlin as maintenance treatment for patients with advanced or recurrent endometrial cancer (EC) who have achieved complete...

Enrolling
Endometrial Cancer
Drug: Navtemadlin
Drug: Navtemadlin Placebo

The purpose of this study is to assess the efficacy and safety of pembrolizumab in combination with concurrent chemoradiation therapy followed by eit...

Active, not recruiting
Lung Neoplasms
Carcinoma, Non-Small-Cell Lung
Drug: Cisplatin
Biological: Pembrolizumab

The goal of this clinical study is to learn more about the study drug, sacituzumab govitecan-hziy, in participants with metastatic (cancer that has s...

Active, not recruiting
Metastatic Solid Tumor
Drug: Sacituzumab Govitecan-hziy

This is a Phase 2/3 study evaluating the safety and efficacy of DM199 in treating participants presenting within 24 hours of Acute Ischemic Stroke (A...

Enrolling
Ischemic Stroke
Stroke
Drug: Recombinant human tissue kallikrein

Trial sponsors

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