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Active trials

16 of 72 total trials
Locations recently updated

A Study of Efficacy and Safety of Ianalumab in Previously Treated Patients With Warm Autoimmune Hemolytic Anemia (VAYHIA)

The purpose of this study is to evaluate efficacy and safety of ianalumab compared to placebo in patients with warm autoimmune hemolytic anemia, who...

Enrolling
Warm Autoimmune Hemolytic Anemia (wAIHA)
Drug: Placebo
Biological: Ianalumab
Locations recently updated

The purpose of this study is to evaluate the effect of two different doses of ianalumab added to eltrombopag to prolong Time to Treatment Failure (TT...

Active, not recruiting
Primary Immune Thrombocytopenia
Biological: Ianalumab
Drug: Eltrombopag

The purpose of this study is to evaluate whether milvexian compared to placebo reduce the risk of recurrent ischemic stroke.

Enrolling
Ischemic Stroke; Ischemic Attack, Transient
Drug: Placebo
Drug: Milvexian

The purpose of this study is to evaluate the efficacy and safety of pemigatinib versus gemcitabine plus cisplatin chemotherapy in first-line treatmen...

Active, not recruiting
Metastatic Cholangiocarcinoma
Unresectable Cholangiocarcinoma
Drug: Gemcitabine
Drug: Cisplatin

The ALLEVIATE-HF study is a prospective, randomized, controlled, blinded, multi-site, interventional, investigational device exemption (IDE) pivotal...

Active, not recruiting
Heart Failure NYHA Class II
Heart Failure NYHA Class III
Device: Reveal LINQ™ Insertable Cardiac Monitor with investigational ALLEVIATE-HF RAMware download
Other: Medication intervention

The purpose of this study is to evaluate the efficacy and safety of 177Lu-PSMA-617 in combination with Standard of Care, versus Standard of Care alon...

Active, not recruiting
Prostatic Neoplasms
Drug: ARDT
Drug: ADT

The purpose of this post-marketing study is to further characterize the long-term outcome of known or potential risks of lutetium (177Lu) vipivotide...

Enrolling
Prostate Cancer
Drug: AAA617

This is a prospective, multicenter, double-blind, placebo-controlled, randomized Phase 3 study. The purpose of the study is to obtain evidence of eff...

Active, not recruiting
Endometrial Cancer
Drug: Matching placebo for selinexor
Drug: Selinexor

Study to compare the safety and efficacy of oregovomab versus placebo, administered in combination with specific cycles of a standard six-cycle chemo...

Active, not recruiting
Ovarian Neoplasms
Fallopian Tube Adenocarcinoma
Drug: Paclitaxel
Biological: Placebo

RADIANCE CAP is a non-randomized study designed to allow for continued access to ultrasound renal denervation therapy via the Paradise System, and to...

Active, not recruiting
Hypertension
Hypertension, Resistant to Conventional Therapy
Device: Renal Denervation

This is an open label, multicenter, single arm phase II study to evaluate the efficacy and safety of ribociclib and ET in patients with locoregional...

Enrolling
Hormone Receptor-positive Breast Cancer
Locoregional Recurrence
Drug: Fulvestrant
Drug: Ribociclib
Locations recently updated

The purpose of this study is to evaluate the effect of two different doses of ianalumab versus placebo in addition to first-line corticosteroids in m...

Enrolling
Primary Immune Thrombocytopenia (ITP)
Biological: Ianalumab
Drug: Placebo

This study evaluates navtemadlin as maintenance treatment for patients with advanced or recurrent endometrial cancer (EC) who have achieved complete...

Enrolling
Endometrial Cancer
Drug: Navtemadlin
Drug: Navtemadlin Placebo

The purpose of this study is to assess the efficacy and safety of pembrolizumab in combination with concurrent chemoradiation therapy followed by eit...

Active, not recruiting
Lung Neoplasms
Carcinoma, Non-Small-Cell Lung
Drug: Cisplatin
Biological: Pembrolizumab

The goal of this clinical study is to learn more about the study drug, sacituzumab govitecan-hziy, in participants with metastatic (cancer that has s...

Active, not recruiting
Metastatic Solid Tumor
Drug: Sacituzumab Govitecan-hziy

This is a Phase 2/3 study evaluating the safety and efficacy of DM199 (rinvecalinase alfa) in treating participants with moderate stroke severity, wh...

Enrolling
Ischemic Stroke
Stroke
Other: Placebo for DM199 Solution for Injection
Drug: Recombinant human tissue kallikrein

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