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Active trials

13 of 65 total trials

A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE

The purpose of this study is to evaluate whether milvexian compared to placebo reduce the risk of recurrent ischemic stroke.

Enrolling
Ischemic Stroke; Ischemic Attack, Transient
Drug: Placebo
Drug: Milvexian

The purpose of this study is to evaluate the efficacy and safety of pemigatinib versus gemcitabine plus cisplatin chemotherapy in first-line treatmen...

Enrolling
Metastatic Cholangiocarcinoma
Unresectable Cholangiocarcinoma
Drug: Cisplatin
Drug: Gemcitabine

The ALLEVIATE-HF study is a prospective, randomized, controlled, blinded, multi-site, interventional, investigational device exemption (IDE) pivotal...

Enrolling
Heart Failure NYHA Class II
Heart Failure NYHA Class III
Device: Reveal LINQ™ Insertable Cardiac Monitor with investigational ALLEVIATE-HF RAMware download
Other: Medication intervention

This is a multicenter, randomized, open-label study of Tumor Treating Fields (TTFields) at 150 kHz to the thorax using the NovoTTF-200T System with I...

Enrolling
Non-small Cell Lung Cancer
Drug: Pembrolizumab (MK-3475) 200 mg
Device: NovoTTF-200T
Locations recently updated

This is a multi-center study in patients with recurrent or metastatic HPV16-positive, PD-L1 positive cervical cancer who has progressed during or aft...

Enrolling
HPV-Related Cervical Carcinoma
HPV-Related Malignancy
Drug: Placebo
Biological: VB10.16

This is a prospective, multicenter, double-blind, placebo-controlled, randomized Phase 3 study. The purpose of the study is to obtain evidence of eff...

Active, not recruiting
Endometrial Cancer
Drug: Matching placebo for selinexor
Drug: Selinexor

Study to compare the safety and efficacy of oregovomab versus placebo, administered in combination with specific cycles of a standard six-cycle chemo...

Active, not recruiting
Ovarian Neoplasms
Fallopian Tube Adenocarcinoma
Drug: Paclitaxel
Drug: Carboplatin

The objective of this post-market trial is to evaluate Endologix AFX endovascular AAA system with anatomical fixation against other approved Endovasc...

Active, not recruiting
Abdominal Aortic Aneurysm
Device: FDA Approved EVAR AAA Graft Systems
Device: AFX EVAR AAA Graft System

RADIANCE CAP is a non-randomized study designed to allow for continued access to ultrasound renal denervation therapy via the Paradise System, and to...

Active, not recruiting
Hypertension
Hypertension, Resistant to Conventional Therapy
Device: Renal Denervation

This is an open label, multicenter, single arm phase II study to evaluate the efficacy and safety of ribociclib and ET in patients with locoregional...

Enrolling
Hormone Receptor-positive Breast Cancer
Locoregional Recurrence
Drug: Fulvestrant
Drug: Anastrozole

This study evaluates navtemadlin as maintenance treatment for patients with advanced or recurrent endometrial cancer (EC) who have achieved complete...

Enrolling
Endometrial Cancer
Drug: Navtemadlin Placebo
Drug: Navtemadlin

The goal of this clinical study is to learn more about the study drug, sacituzumab govitecan-hziy, in participants with metastatic (cancer that has s...

Active, not recruiting
Metastatic Solid Tumor
Drug: Sacituzumab Govitecan-hziy

This is a Phase 2/3 study evaluating the safety and efficacy of DM199 in treating participants presenting within 24 hours of Acute Ischemic Stroke (A...

Enrolling
Ischemic Stroke
Stroke
Drug: Recombinant human tissue kallikrein

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