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Pontificia Universidad Catolica de Chile | Centro de Investigacion Clinica UC-CICUC

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Active trials

9 of 53 total trials

A Prospective, Randomized, Controlled Trial to Test Safety and Effectiveness of Unilateral Exablate MR-guided Focused Ultrasound Subthalamotomy in Patients With Early-Stage Parkinson's Disease

This prospective, randomized, multicenter study aims to evaluate in Early-Stage Parkinson's Disease (ESPD) patients the safety and effectiveness of t...

Enrolling
Parkinson Disease
Procedure: Exablate MRgFUS subthalamotomy
Drug: Best Medical Treatment

This is an open-label, multicenter, extension study. Patients who are receiving clinical benefit from atezolizumab monotherapy or atezolizumab in com...

Active, not recruiting
Cancer
Drug: Emactuzumab
Drug: Niraparib

The Purpose of the Study is to Compare the Efficacy and Safety of BMS-986489 (Anti-fucosyl-GM1+ Nivolumab Fixed Dose Combination) in Combination with...

Enrolling
Extensive-Stage Small Cell Lung Cancer
Drug: Carboplatin
Drug: Etoposide

The purpose of this study is to compare the efficacy of Nivolumab and Relatlimab in combination with chemotherapy to Pembrolizumab with Chemotherapy...

Enrolling
Non-small Cell Lung Cancer
Drug: Relatlimab
Drug: Nivolumab

The purpose of this study is to evaluate the effectiveness and safety of deucravacitinib compared with placebo in an active moderate to severe System...

Enrolling
Systemic Lupus Erythematosus
Drug: Deucravacitinib
Other: Placebo

The primary objective of the study is to determine the effect of seralutinib on improving exercise capacity in subjects with WHO Group 1 PAH who are...

Active, not recruiting
Pulmonary Arterial Hypertension
Drug: Placebo
Drug: Seralutinib

This open-label extension study will evaluate the long-term safety, tolerability and efficacy of orally inhaled seralutinib in subjects who have comp...

Enrolling
Pulmonary Arterial Hypertension
Device: Gereic Dry Powder Inhaler
Drug: Seralutinib

The purpose of this study was to evaluate the efficacy and safety of pembrolizumab plus epacadostat compared to sunitinib or pazopanib in participant...

Active, not recruiting
Renal Cell Carcinoma (RCC)
Drug: Pazopanib
Drug: Epacadostat
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Researchers are looking for new ways to treat people with endometrial cancer (EC) who have previously received treatment with platinum based therapy...

Enrolling
Endometrial Cancer
Drug: Paclitaxel
Drug: Nab-paclitaxel

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