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Prisma Health | Upstate Greenville Memorial Cardiac Research

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Lenalidomide
nivolumab
MT-5111
SHR-A1904
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Gemcitabine
MT-6402
Folate
Atezolizumab

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Active trials

31 of 79 total trials

(HALT) Embrace Hydrogel Embolic System (HES) Study of Embolization in Peripheral Arterial Bleeds

To evaluate the safety and effectiveness of Embrace Hydrogel Embolic System for the transcatheter embolization of peripheral arterial bleeds.

Enrolling
Arterial Bleeding in Solid Organs and Peripheral Arteries
Device: Embrace HES including Instylla™ Delivery Kit and Instylla™ Microcatheter

This is a Phase 4, U.S. only, multi-center study using a 7-day therapeutic response dose (TRD) of commercial Sucraid® to assess the response of treat...

Enrolling
CSID
Congenital Sucrase-Isomaltase Deficiency
Biological: Sucraid (sacrosidase) Oral Solution 8500 IU/mL

This is a prospective, multicenter, single arm study designed to evaluate the safety and efficacy of the Temporary Bare Spur Stent System (Spur Stent...

Enrolling
Critical Limb Ischemia
Peripheral Arterial Disease
Device: Bare Temporary Spur Stent System

The primary objective of the Phase 2 portion of the study is to characterize the clinical activity of maintenance therapy with GRT-C901/GRT-R902 (pat...

Active, not recruiting
Colorectal Neoplasms
Drug: Ipilimumab
Drug: Atezolizumab

This clinical trial is a Phase 2/3 study that will evaluate the efficacy and safety of etavopivat and test how well etavopivat works compared to plac...

Enrolling
Sickle Cell Disease
Drug: Placebo Tablets
Drug: Etavopivat Tablets High dose

B-cell Lymphoma is an aggressive and rare cancer of a type of immune cells (a white blood cell responsible for fighting infections). Classic Follicul...

Enrolling
Classic Follicular Lymphoma
Diffuse Large B-Cell Lymphoma
Drug: Epcoritamab

The study (dose escalation/expansion) is being conducted to assess the safety and tolerability of SHR-A1904 in subjects with advanced solid tumors, a...

Enrolling
Advanced Solid Tumors
Drug: SHR-A1904
Recently updated

This trial studies how well tucatinib works for solid tumors that make either more HER2 or a different type of HER2 than usual (HER2 alterations) The...

Active, not recruiting
Uterine Cervical Neoplasms
Uterine Neoplasms
Drug: fulvestrant
Drug: trastuzumab
Recently updated

Participants in this study will have diffuse large B-cell lymphoma (DLBCL) that has come back or not gotten better with treatment. The trial will stu...

Active, not recruiting
Diffuse Large B-cell Lymphoma
Drug: Rituximab
Drug: Lenalidomide

The purpose of the study is to compare the effects, good and/or bad, of a treatment for removing kidney stones called the SURE procedure for stone ev...

Active, not recruiting
Renal Stone
Urolithiasis
Device: SURE
Device: Standard Ureteroscopy (Basketing)

To collect post-approval data comparing the safety and effectiveness of CraniSeal Dural Sealant to DuraSeal Dural Sealant. The study has been powered...

Enrolling
Leak, Cerebrospinal Fluid
Device: DuraSeal
Device: CraniSeal

The purpose of this study is to evaluate the safety and efficacy of embolization of the middle meningeal artery (MMA) using the Onyx™ Liquid Embolic...

Active, not recruiting
Subdural Hematoma
Device: Surgical Management + Treatment
Device: Treatment

Our aim is to conduct a multi-center, Bayesian, randomized clinical trial to evaluate the primary technical success of coils and vascular plugs for p...

Enrolling
High-grade Splenic Injuries
Device: Splenic artery embolization with vascular embolic coils or plugs

The purpose of this trial is to generate clinical evidence related to key performance outcomes of Endurant II/IIs Stent Graft Systems verses Gore Exc...

Enrolling
Abdominal Aortic Aneurysm >= 5.0 Centimeters in Female (Disorder)
Abdominal Aortic Aneurysm
Device: Gore Excluder or Gore/ Excluder Conformable AAA Endoprosthesis
Device: Medtronic Endurant II or Endurant IIs Stent Graft System

The purpose of this prospective, multicenter study is to assess the safety and efficacy of tibial neuromodulation using the Medtronic Tibial Neuromod...

Active, not recruiting
Overactive Bladder
Device: Medtronic Implantable Tibial Neuromodulation (TNM) System

This trial is being conducted in order to compare angiographic outcomes in patients receiving 0.014-0.0155" platinum framing and filling coils (large...

Active, not recruiting
Cerebral Aneurysm
Procedure: Coil Embolization with larger Diameter Coils
Procedure: Coil Embolization with Standard Diameter Coils

The study is a multi-center, open-label, randomized active controlled study of subjects with locally advanced pancreatic adenocarcinoma which is unre...

Enrolling
Locally Advanced Pancreatic Cancer
Device: RenovoCath
Drug: nab-paclitaxel

This is a multi-center, prospective, propensity matched twin armed study conducted on 50 patients in the experimental arm followed for 18 months afte...

Enrolling
Wide Neck Intracranial Aneurysms
Intracranial Aneurysms
Device: Kaneka i-ED coil

The purpose of this post market study is to evaluate the performance and safety of LiquiBand® Exceed™ and LiquiBand® Rapid™ for closure of surgical i...

Active, not recruiting
Surgical Wound
Device: LiquiBand Rapid
Device: LiquiBand Exceed

This is a prospective, multi-center, two-arm, randomized trial to quantify the performance of the EchoMark®/EchoSure® System for AVF diagnostic ultra...

Enrolling
Diabetes
End Stage Renal Disease
Device: EchoMark/EchoSure
Procedure: Standard of Care

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