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Proactive Clinical Research, LLC | Fort Lauderdale, FL

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Top conditions

Top treatments

TQJ230
Obeldesivir
PF-07817883
Pelacarsen
Olpasiran
Tenapanor
Ibuzatrelvir
sodium
Inclisiran
Baloxavir Marboxil

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Active trials

8 of 20 total trials

A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults

This is a 26-week, multi-center, randomized, double-blind, placebo-controlled study with a 4-week treatment-free Safety Follow-up period to assess th...

Enrolling
Chronic Idiopathic Constipation (CIC)
Drug: Tenapanor 50 mg BID
Drug: Tenapanor 5 mg BID

CKJX839D12302 is a pivotal Phase III study designed to test the hypothesis that treatment with inclisiran sodium 300 milligram (mg) subcutaneous (s.c...

Active, not recruiting
Primary Prevention of Atherosclerotic Cardiovascular Disease
Drug: Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL
Drug: Placebo in 1.5ml

The purpose of the study is to learn about how effective, safe, and tolerable the Clostridioides difficile (C. difficile) vaccine is in decreasing th...

Enrolling
Clostridioides Difficile Associated Disease
Biological: C.difficile vaccine
Other: Saline Placebo
Locations recently updated

The purpose of the study is to evaluate whether ibuzatrelvir is effective and safe in adults and adolescents with COVID-19 who do not need to be in t...

Enrolling
COVID-19 SARS-CoV-2 Infection
Drug: placebo
Drug: ibuzatrelvir

Study CTQJ230A12303 is a randomized, double-blind placebo-controlled, Phase IIIb study to evaluate the efficacy, safety and tolerability of pelacarse...

Active, not recruiting
Elevated Lp(a) and Established Atherosclerotic Cardiovascular Disease
Drug: TQJ230
Drug: Placebo
Locations recently updated

The primary objective is to evaluate the effect of olpasiran, compared to placebo, on the risk for coronary heart disease death (CHD death), myocardi...

Enrolling
Cardiovascular Disease
Drug: Olpasiran
Drug: Placebo

This non-randomized, rollover extension study will provide post-trial access to pelacarsen (TQJ230) to participants who have successfully completed e...

Enrolling
Atherosclerotic Cardiovascular Disease
Drug: Pelacarsen (TQJ230)

The overall objective of the RESTORATiVE303 study is to evaluate the safety and the Clostridioides difficile infection (CDI) recurrence rate at Week...

Enrolling
CDI
C.Difficile Diarrhea
Biological: Placebo
Biological: VE303

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