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PSEG Centro de Pesquisa Clinica | Sao Paulo, Brazil

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Top conditions

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SAR441344
Frexalimab
Superoxide
Tofersen
Omaveloxolone
BIIB141
BIIB067

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Active trials

5 of 5 total trials

A Study of BIIB067 (Tofersen) Initiated in Clinically Presymptomatic Adults With a Confirmed Superoxide Dismutase 1 Mutation (ATLAS)

The primary objective of this study is to evaluate the efficacy of tofersen in presymptomatic adult carriers of a superoxide dismutase 1 (SOD1) mutat...

Active, not recruiting
Amyotrophic Lateral Sclerosis Associated With a SOD1 Gene Mutation
Drug: Tofersen
Drug: Placebo

The purpose of this study is to evaluate the efficacy and safety of telitacicept in the treatment of generalized myasthenia gravis.

Enrolling
Generalized Myasthenia Gravis
Drug: Placebo
Biological: Telitacicept

In this study, researchers will learn more about the effects and safety of BIIB141, also known as omaveloxolone or SKYCLARYS®. This drug has been app...

Enrolling
Friedreich Ataxia
Drug: Placebo
Drug: Omaveloxolone

The purpose of each study is to independently measure the annualized relapse rate (ARR) with administration of frexalimab compared to a daily oral do...

Enrolling
Multiple Sclerosis
Drug: Activated charcoal
Drug: Cholestyramine

The purpose of this randomized, double-blind, placebo-controlled, parallel group study is to determine the efficacy of frexalimab in delaying the dis...

Enrolling
Multiple Sclerosis
Drug: Frexalimab
Drug: Placebo

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