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QUEST Research Institute | Farmington Hills, MI

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APL-130277
Carbidopa
Levodopa
CVN424
LY3002813
Prasinezumab
Gantenerumab
ND0612
Donanemab
ABBV-916

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Active trials

25 of 75 total trials

A Clinical Study of NLY01 in Patient's With Early Parkinson's Disease

This is a phase 2 study designed to assess the safety, tolerability and efficacy of NLY01 in subjects with early untreated Parkinson's disease (PD)....

Active, not recruiting
Parkinson Disease
Drug: NLY01
Drug: Vehicle

This is a multi-center, international, open-label, safety study of ND0612, a solution of levodopa/carbidopa (LD/CD) delivered via a pump system as a...

Active, not recruiting
Parkinson's Disease
Drug: ND0612

This is a Phase 2, double-blind, parallel-group, placebo-controlled study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and...

Enrolling
Multiple System Atrophy (MSA)
Drug: ONO-2808
Drug: Placebo

This is a Phase 2a study to assess the safety and tolerability of TPN-101 patients with PSP.

Active, not recruiting
Progressive Supranuclear Palsy
Drug: Placebo
Drug: TPN-101, 100 mg/day

This study will investigate different donanemab dosing regimens and their effect on the frequency and severity of ARIA-E in adults with early symptom...

Enrolling
Alzheimer's Disease
Mental Disorders
Drug: Placebo
Drug: Donanemab

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.Additional part...

Active, not recruiting
Alzheimer Disease
Drug: Donanemab
Drug: Placebo

Alzheimer's disease (AD) is a progressive, irreversible neurological disorder and is the most common cause of dementia in the elderly population. Cli...

Enrolling
Alzheimer's Disease (AD)
Drug: Placebo
Drug: ABBV-916

PROSPER trial is a trial to assess the efficacy of FNP-223 in slowing disease progression in participants with PSP as measured by the PSP Rating Scal...

Enrolling
Progressive Supranuclear Palsy
Drug: FNP-223
Drug: Placebo

The purpose of the study is to assess the safety and efficacy of increasing doses of IPN10200 with the aim to evaluate the Pharmacodynamics (PD) prof...

Active, not recruiting
Spasticity
Biological: Dysport
Biological: IPN10200

This is a 12-week, double-blind, placebo-controlled, randomized, parallel-group, multicenter study of the safety and efficacy of JZP385 in the treatm...

Active, not recruiting
Essential Tremor
Drug: JZP385
Other: Placebo

In this study, researchers will learn more about a study drug called BIIB122 in participants with early-stage Parkinson's disease (PD). In this study...

Enrolling
Parkinson Disease
Drug: BIIB122
Drug: BIIB122-Matching Placebo

This is a multicenter, randomized, double-blind, placebo-controlled study that will evaluate the efficacy and safety of intravenous (IV) prasinezumab...

Active, not recruiting
Parkinsons Disease
Drug: Prasinezumab
Drug: Placebo
Locations recently updated

This multicenter, randomized, double-blind, placebo-controlled, Phase 2 study will evaluate the efficacy of intravenous prasinezumab (RO7046015/PRX00...

Active, not recruiting
Parkinson's Disease
Drug: RO7046015
Drug: Placebo

The primary objective of this study is to evaluate the safety and tolerability of single and multiple doses of BIIB094 administered via intrathecal (...

Active, not recruiting
Parkinson's Disease
Drug: Placebo
Drug: BIIB094

This is a multi-center, randomized, double blind, adaptive, parallel-group, placebo controlled Phase 1b study to evaluate the safety, tolerability, p...

Enrolling
Parkinson Disease
Drug: RO7486967
Drug: Placebo

ORION Trial is a trial to evaluate the efficacy and safety of AMX0035 in participants with Progressive Supranuclear Palsy (PSP), consisting of a rand...

Enrolling
PSP
Neurodegenerative Diseases
Other: Placebo
Drug: AMX0035

The purpose of this study is to evaluate the safety, tolerability, immunogenicity, pharmacokinetics, and pharmacodynamics of multiple-ascending intra...

Enrolling
Alzheimers Disease
Drug: Placebo
Drug: RO7126209

This is a multicenter, 12-week, placebo-controlled clinical trial of CVN424 150 milligrams (mg) tablets in early, untreated Parkinson's Disease (PD)....

Enrolling
Parkinson's Disease
Drug: Placebo
Drug: CVN424 150 mg

This is a multi-center, randomized, double-blind, double-dummy, active controlled clinical Study. Following a screening period, eligible subjects wil...

Active, not recruiting
Parkinson's Disease
Combination Product: ND0612 Solution for SC infusion
Drug: Placebo for Oral IR-LD/CD

The purpose of this randomized, double-blind, placebo-controlled study is to assess the efficacy of BIA 28-6156 over placebo in delaying clinical mea...

Enrolling
Parkinson's Disease
Drug: Placebo
Drug: BIA 28-6156 60 mg

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