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Quotient Sciences | Nottingham

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anle138b
BMS-986165
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Active trials

7 of 65 total trials

A Study to Assess the Effect of Famotidine on the Drug Levels of Afimetoran in Healthy Participants

The purpose of this study is to confirm there is no significant effect of gastric pH changes of famotidine on the drug levels of afimetoran in health...

Enrolling
Healthy Volunteers
Drug: Afimetoran
Drug: Famotidine

The purpose of this study is to evaluate novel KarX and KarT prototypes versus the KarXT and KarX-EC reference following single doses, and to explore...

Enrolling
Healthy Volunteers
Drug: Trospium Chloride
Drug: Xanomeline Enteric Capsule

This trial is intended to investigate the mass balance, metabolism, and basic pharmacokinetics of BI 1819479 (C-14) (Part A) and to investigate the a...

Enrolling
Healthy
Drug: BI 1819479 (C-14)
Drug: [14C]BI 1819479

This is a two-part, single centre, double-blind (within cohorts), randomised, placebo-controlled, single (Part 1) and multiple (Part 2) ascending sub...

Enrolling
Overweight
Healthy Volunteers
Drug: GUB014295-PLACEBO
Drug: GUB014295

This is a single-dose, phase 1 open-label study to determine the mass balance recovery and metabolic profiling and identification for intravenous (IV...

Enrolling
ADME
Drug: [14C]Xeruborbactam

This is a Phase I, double-blind, randomised, two-part, single-ascending dose (Part 1) and multiple-ascending dose (Part 2) study of NM-101 in healthy...

Not yet enrolling
Parkinson Disease
Drug: NM-101
Drug: Placebo

This is a single-centre, participant- and investigator-blind, randomised, placebo controlled, single ascending dose study to assess the safety, toler...

Enrolling
Malaria, Falciparum
Drug: MMV055 Dose 6
Combination Product: MMV055/MM371 Combo 2

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