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BI 685509
MB-102
Calcifediol
PF-07321332
Ritonavir
Relmapirazin
Finerenone
Paricalcitol
MK-8527-008
sodium chloride

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Active trials

6 of 24 total trials

A Study of MK-8527 in Participants With Moderate and Severe Renal Impairment (MK-8527-008)

The goal of this study is to evaluate the effect of moderate and severe renal impairment (RI) on the pharmacokinetics (PK), safety, and tolerability...

Enrolling
Renal Impairment
Drug: MK-8527

Primary Objectives* To assess the safety and tolerability of RGLS8429* To assess the impact of RGLS8429 on ADPKD biomarkersSecondary Objectives* To a...

Enrolling
ADPKD
Polycystic Kidney, Autosomal Dominant
Drug: Placebo
Drug: RGLS8429

This study is open to adults who are at least 18 years old and have a body mass index (BMI)bof 27 kg/m2 or more. People can take part if they have ca...

Enrolling
Obesity
Drug: Placebo
Drug: survodutide

Researchers are looking for a better way to treat people who have non-diabetic chronic kidney disease (non-diabetic CKD). The trial treatment, finere...

Active, not recruiting
Non-diabetic Chronic Kidney Disease
Drug: Finerenone (BAY94-8862)
Drug: Placebo

The objective of this study is to establish that the MB-102 transdermal fluorescence-measured Glomerular Filtration Rate (GFR) using the MediBeacon®...

Active, not recruiting
Kidney Failure
Kidney Diseases
Device: MediBeacon Transdermal Glomerular Filtration Rate Measurement System (TGFR)
Drug: MB-102

This study is conducted to see if ziltivekimab reduces the risk of having cardiovascular events (for example heart attack and stroke) in people with...

Enrolling
Chronic Kidney Disease
Inflammation
Drug: Placebo (Ziltivekimab B)
Drug: Placebo (Ziltivekimab C)

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