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Active trials

6 of 33 total trials

A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

The purpose of this study is to evaluate the safety, tolerability, and effect on Albuminuria of MZE829 in Adults with APOL1 Kidney Disease.

Enrolling
Proteinuric Kidney Disease
Drug: MZE829

This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter study designed to evaluate the efficacy and safety of praliciguat in adu...

Enrolling
Focal Segmental Glomerulosclerosis
Drug: Praliciguat
Other: Placebo

The purpose of this study is is to evaluate the efficacy and safety of veverimer in treating adults with moderate-to-severe chronic kidney disease (C...

Enrolling
CKD
Metabolic Acidosis
Drug: Placebo
Drug: Veverimer

This study will evaluate safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of single ascending doses (SAD) and multiple ascendin...

Enrolling
Chronic Kidney Disease
Drug: Placebo
Drug: AZD4248

This study is open to adults with chronic kidney disease (CKD) that is at risk of getting worse. People who have taken a specific type of medication...

Active, not recruiting
Chronic Kidney Disease
Drug: Vicadrostat
Drug: Empagliflozin

This study is researching experimental drugs called ALN-ANG3 and evinacumab (called "study drugs"). The study is focused on participants who have dia...

Enrolling
Diabetic Kidney Disease (DKD)
Drug: Evinacumab
Drug: ALN-ANG3 placebo

Trial sponsors

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