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Retina Centre of Ottawa | Ottawa, Canada

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Active trials

3 of 8 total trials

A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections of Vonaprument (Formerly ANX007) in Participants With Geographic Atrophy (GA) (ARCHER II)

The primary purpose of the study is to determine if IVT injections of vonaprument every month reduce vision loss in participants with GA secondary to...

Active, not recruiting
Geographic Atrophy
Drug: Vonaprument
Other: Sham Administration

ABBV-RGX-314 (also known as RGX-314) is being developed as a novel one-time gene therapy for the treatment of neovascular (wet) age-related macular d...

Enrolling
Wet Age-related Macular Degeneration
WetAMD
Genetic: ABBV-RGX-314 Dose 1
Biological: Aflibercept (EYLEA®)
Locations recently updated

Neovascular age-related macular degeneration (nAMD), also known as "wet" AMD, is the abnormal growth of new blood vessels in the light-sensitive tiss...

Enrolling
Neovascular Age-related Macular Degeneration
Drug: Surabgene Lomparvovec (ABBV-RGX-314)
Drug: Ranibizumab Control

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