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Royal North Shore Hospital | Renal Medicine - Renal Research Unit

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gemcitabine
vinorelbine
cisplatin
5-fluorouracil
Cisplatin
Avelumab
67Cu
Dapagliflozin
Levofloxacin
Amoxicillin-clavulanate

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Active trials

7 of 81 total trials

A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

Phase 1/2, dose escalation and expansion study designed to evaluate the safety and tolerability of neladalkib (NVL-655), determine the recommended ph...

Enrolling
Locally Advanced Solid Tumor
Metastatic Solid Tumor
Drug: Neladalkib (NVL-655)

DMX-200 (repagermanium) is a C-C chemokine receptor type 2 (CCR2) inhibitor that, when administered concurrently with an ARB, is designed to inhibit...

Enrolling
FSGS
Drug: DMX-200
Drug: Placebo

This is a prospective, open label, multicenter, single arm, first in human clinical study.Patients with infra-inguinal peripheral arterial disease ap...

Enrolling
Superficial Femoral Artery Stenosis
Popliteal Artery Stenosis
Device: ChampioNIR Ridaforolimus Eluting Peripheral Stent System

This is a randomized, double-blind, placebo-controlled, parallel-group, international, Phase 3 study in patients with newly diagnosed H3 K27M-mutant...

Enrolling
Glioma
H3 K27M
Other: Placebo
Drug: Dordaviprone (ONC201) + Placebo

The purpose of this study is to evaluate the safety, tolerability, and preliminary activity of SQ3370 in patients with advanced solid tumors.

Enrolling
Cancer
Drug: SQ3370

This is a multicenter, randomized, open-label, Phase 3 study in participants with newly diagnosed multiple myeloma to evaluate the benefits of teclis...

Enrolling
Multiple Myeloma
Drug: Lenalidomide
Drug: Teclistamab

Rationale:Sodium glucose co transporter 2 (SGLT2) inhibitors are a relatively new class of agents, originally developed as oral antihyperglycemic dru...

Invitation-only
Kidney Failure
Death
Drug: Dapagliflozin 10 mg/day (oral)
Drug: Placebo

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