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Royal North Shore Hospital | Renal Medicine - Renal Research Unit

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gemcitabine
vinorelbine
cisplatin
5-fluorouracil
Cisplatin
Avelumab
67Cu
Dapagliflozin
Levofloxacin
Amoxicillin-clavulanate

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Active trials

10 of 89 total trials

131I-TLX-101 for Treatment of Newly Diagnosed Glioblastoma (IPAX-2)

This is an open label, single arm, parallel-group, multicentre, and dose finding study to evaluate the safety of ascending radioactive dose levels of...

Enrolling
Glioblastoma
Neoplastic Disease
Drug: 131I-IPA

Phase 1/2, dose escalation and expansion study designed to evaluate the safety and tolerability of neladalkib (NVL-655), determine the recommended ph...

Enrolling
Locally Advanced Solid Tumor
Metastatic Solid Tumor
Drug: Neladalkib (NVL-655)

DMX-200 (repagermanium) is a C-C chemokine receptor type 2 (CCR2) inhibitor that, when administered concurrently with an ARB, is designed to inhibit...

Enrolling
FSGS
Drug: DMX-200
Drug: Placebo

This first-in-human (FIH) trial for BNT116 aims to establish the safety profile and a safe dose for BNT116 monotherapy as well as for BNT116 in combi...

Enrolling
Non-Small Cell Lung Cancer
Biological: Bispecific antibody for PD-L1 and VEGF-A
Drug: Docetaxel

This is a prospective, open label, multicenter, single arm, first in human clinical study.Patients with infra-inguinal peripheral arterial disease ap...

Enrolling
Superficial Femoral Artery Stenosis
Popliteal Artery Stenosis
Device: ChampioNIR Ridaforolimus Eluting Peripheral Stent System

The purpose of this study is to check that a new insulin pump, called NMX8, is safe when used with a continuous glucose monitoring sensor called Disp...

Not yet enrolling
Type 1 Diabetes Mellitus
Type 2 Diabetes Mellitus
Device: MiniMed™ NMX8-AID System with DS5™

This is a randomized, double-blind, placebo-controlled, parallel-group, international, Phase 3 study in patients with newly diagnosed H3 K27M-mutant...

Enrolling
Glioma
H3 K27M
Other: Placebo
Drug: Dordaviprone (ONC201) + Placebo

This is a multicenter, randomized, open-label, Phase 3 study in participants with newly diagnosed multiple myeloma to evaluate the benefits of teclis...

Enrolling
Multiple Myeloma
Drug: Lenalidomide
Drug: Teclistamab

This global clinical trial which evaluates the efficacy and safety of TLX101-Tx, an investigational radiopharmaceutical therapy, in combination with...

Enrolling
Glioblastoma Multiforme (GBM) WHO Grade IV
Glioblastoma Multiforme, Adult
Radiation: TLX101-Tx
Combination Product: TLX-101-Tx + Lomustine

Rationale:Sodium glucose co transporter 2 (SGLT2) inhibitors are a relatively new class of agents, originally developed as oral antihyperglycemic dru...

Invitation-only
Kidney Failure
Death
Drug: Dapagliflozin 10 mg/day (oral)
Drug: Placebo

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