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Sahlgrenska University Hospital | Gothia Forum - Clinical Trial Center

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Upadacitinib
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Durvalumab
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Active trials

28 of 275 total trials

A 3-Arm Study on G7 Acetabular Cup With Echo BiMetric Stem in Total Hip Arthroplasty

The study is designed to compare three articulation options in terms of osteolysis, patient satisfaction, clinical and radiographic outcomes (Oxford...

Active, not recruiting
Arthritis
Pain
Procedure: Hip Arthroplasty
Locations recently updated

Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. Non-small cell lung cancer (NSCLC) is a solid tumor,...

Enrolling
Non Small Cell Lung Cancer
Drug: Docetaxel
Biological: Telisotuzumab Vedotin

This is a multicenter, international open-label extension study of ATB200/AT2221 in adult subjects with late-onset Pompe disease (LOPD) who completed...

Active, not recruiting
Pompe Disease (Late-onset)
Biological: ATB200
Drug: AT2221

This study will be conducted to evaluate the efficacy of lecanemab in participants with early Alzheimer's disease (EAD) by determining the superiorit...

Active, not recruiting
Early Alzheimer's Disease
Drug: Placebo
Drug: Lecanemab

B-cell Lymphoma is an aggressive and rare cancer of a type of immune cells (a white blood cell responsible for fighting infections). The purpose of t...

Enrolling
Diffuse Large B-Cell Lymphoma
Drug: Epcoritamab
Drug: Cyclophosphamide

This study consists of two periods. The objective of Period 1 is to evaluate the efficacy of upadacitinib in combination with a 26-week corticosteroi...

Active, not recruiting
Giant Cell Arteritis (GCA)
Drug: Upadacitinib
Other: Placebo

The objective of this study is to assess the efficacy and safety of upadacitinib combined with topical corticosteroids (TCS) for the treatment of ado...

Invitation-only
Atopic Dermatitis
Drug: Placebo
Drug: Upadacitinib

This is a Phase III, international, multicentre, randomised, double-blinded placebo controlled trial, evaluating the efficacy and safety of ADT +/- d...

Enrolling
Prostate Cancer Metastatic
Drug: Androgen deprivation therapy
Drug: Darolutamide 300 mg

The specific study aim is to determine whether a 12-week digitally delivered behavior change intervention for patients with peripheral artery disease...

Active, not recruiting
Intermittent Claudication
Device: A PAD-specific smartphone application (e-intervention) developed for patients with Peripheral Artery Disease

A Phase 3b research study to consolidate the data that ivosidenib is safe and effective in adult patients with previously treated, locally advanced,...

Enrolling
Cholangiocarcinoma
Drug: Ivosidenib Oral Tablet

This program initially aims to recruit 1300 breast cancer patients from a large number of hospitals across Europe. Eligible patients are those who ar...

Enrolling
Metastatic Breast Cancer
Procedure: metastatic lesion biopsy

This is a Phase 1/2a, dose-escalation, multicenter, first-in-human, consecutive-cohort, open-label study of BI-1808, as a single agent and in combina...

Enrolling
Advanced Malignancies
Drug: Pembrolizumab (KEYTRUDA® ) 25 Mg/mL Solution for Injection
Drug: BI-1808

This is a first-in-human clinical, open label, non-randomized, prospective investigation to assess the initial safety and performance of the COPLA® c...

Enrolling
Cartilage or Osteochondral Defects in the Knee
Device: COPLA® cartilage implant

The aim of the clinical trial is to evaluate the EndoRotor®'s ability to completely remove areas of Barrett's esophagus considered refractory after 3...

Enrolling
Barrett's Esophagus With Dysplasia
Device: EndoRotor Mucosal Resection System
Device: Continued Ablation

The goal of this pilot safety and tolerability study is to determine whether the novel CytaCoat LIP (Lubricious Infection Prevention) Foley catheter...

Enrolling
Tolerability of the CytaCoat LIP Foley Catheter
Safety of the CytaCoat LIP Foley Catheter
Device: Drainage of the bladder by indwelling Foley catheter

Uveal melanoma is the most common primary intraocular malignancy in adults. Despite successful control of the primary tumour, metastatic disease will...

Active, not recruiting
Liver Metastases
Uveal Melanoma
Drug: Nivolumab
Drug: Ipilimumab

To evaluate the efficacy and safety of oral masitinib versus placebo in the treatment of patients with primary progressive or secondary progressive m...

Enrolling
Progressive Multiple Sclerosis
Drug: Placebo
Drug: Masitinib (4.5)

The study intends to compare standard ischemic cold static storage (ICSS) of retrieved hearts intended to be transplanted, to non-ischemic heart pres...

Active, not recruiting
Heart Transplantation
Device: Standard ICSS
Device: XVIVO heart preservation devices

Advanced prosthetic devices are currently controlled by electromyography (EMG) signals generated by patient's stump muscles and recorded by surface e...

Enrolling
Upper Limb Amputation
Device: OHMG

Patients with transfemoral amputations (TFA) frequently experience problems related to the use of socket-suspended prostheses 1-3. These problems inc...

Active, not recruiting
Transfemoral Amputation
Device: OPRA Implant System

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